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Shire Global



Championing Responsibility

Annual Responsibility Review 2017


Chief Executive Officer's Letter

Our focus on patients has never been stronger.

Our Responsibility strategy, focused on patients and those who care for them, was created to have a strong positive impact on our business and society – from serving patients, to supporting our communities, to protecting our environment.

Flemming Ornskov, MD, MPH

2017 Performance Highlights



invested in R&D efforts during 2017



patients supported by U.S. Patient Services



patients received financial assistance through our co-pay and Patient Assistance Programs in the United States



hours of volunteer time to SeriousFun Children's Network camps and programs



programs in our clinical research and development pipeline as of December 31, 2017



spent on small businesses in the U.S. as part of our Supplier Diversity Program

Our Responsibility Strategy

In 2017, we developed our first comprehensive Responsibility strategy, which outlines detailed commitments and goals to be achieved by 2025. Our strategy of nine commitments covers engaging our people to operating in a responsible and sustainable way all in service to patients and those who care for them. Read more in the report.

Responsibility at shire: ethics and integrity; efficiency, innovation, growth, people; supporting patients, people and culture, sustainable operations; rare disease patients and those who care for them

Supporting Patients

Supporting patients is at the heart of being a champion for patients. Beyond discovering and developing medicines, we are committed to dramatically shortening the time to diagnosis for rare diseases. We aim to support patients along the entire patient journey, from conducting clinical trials to managing their care through the use of innovative digital technologies and beyond.


Our Commitments through 2025

  • Accelerate rare disease diagnosis
  • Lead in clinical trial transparency
  • Provide the best experience for patients and those who care for them throughout their entire journey

Supporting patient and local communities

2017 marked the second year of our partnership with SeriousFun Children’s Network and its 30 camps and programs around the world. Shire’s $3 million commitment, $1 million annually for three years, enables nearly 1,000 children to attend these life-changing camps.

People and Culture

To serve our patients and communities effectively, Shireemployees must feel empowered and inspired, knowing their efforts arehaving a meaningful impact within a workplace that providesopportunities for professional success and fulfillment. To support them,we nurture a sense of purpose to what we do every day, in a safe andinclusive environment in which all people are treated equally andfairly.

Our Commitments through 2025

  • Engage our employees in our purpose, priorities and commitments
  • Foster a company culture of development and inclusion
  • Establish a culture of best-in-class safety and wellbeing

Employee Volunteering

On October 13, 2017, Shire hosted its third annual Global Day of Service


Employees volunteered


Hours served in total


Charities in partnership with Shire


Global locations where activities were held

Sustainable Operations

Managing sustainable operations – from sourcing and manufacturing responsibly, to delivering safe and effective medicines, to using our natural resources carefully – helps ensure that our patients receive the treatments they need to lead healthier lives.

Our Commitments through 2025

  • Reduce our impact on the natural world
  • Eliminate the use of substances of very high concern
  • Ensure supplier commitment to responsibility

Environmental Management

We launched a Global Energy Management program in 2017 to reduce energy and water use and associated greenhouse gas emission as well as significantly improve operational efficiencies. We identified more than 65 resource conservation measures that are expected to save over $1.5 million in 2018.


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