Animal studies are essential to characterize the biological actions of new drugs and to safeguard the volunteers and patients involved in clinical trials. For these reasons, regulatory authorities around the world require pharmaceutical companies to thoroughly evaluate new products in animals during the drug development process. Shire is committed to the principle of the 3Rs in its use of experimental animals: Reduction (of the number of animals used), Replacement (with alternate methods such as cell culture) and Refinement (of the techniques), as advances in science permit.
Shire’s use of animals in research is closely monitored and Shire is sensitive to the well-being and humane treatment of animals. We endeavor to ensure that appropriate standards of animal welfare and ethics are employed by Shire and any Contract Research Organizations that carry out programs of work on our behalf.