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Shire Global

Who We Are

At Shire, we are champions for people around the world who are struggling with rare diseases – they are at the center of everything we do.

Focusing on a Significant Unmet Medical Need

Rare diseases, most of which are genetic and are present throughout a person's entire life, pose a significant medical and economic burden for patients, communities and healthcare systems. There are more than 7,000 known rare diseases, including Hemophilia, Hereditary Angioedema (HAE), Gaucher disease, Hunter Syndrome, and many forms of rare cancer, and an estimated 350 million people worldwide are living with one.1

These figures do not reflect the untold number of family members and friends who watch a loved one struggle with health challenges that, in many cases, cannot be adequately addressed today, especially considering nearly half of the time these loved ones are children. What's more, patients with rare diseases commonly experience delays to diagnosis, which can lead to serious consequences for their health and the wider healthcare system.

Innovation and Collaboration Will Lead to Breakthrough Progress

This unmet need drives our unique model for innovation, which is a mix of internal knowledge, capabilities and research, combined with collaborations with external partners, patients, doctors, caregivers and advocacy groups, and supplemented by M&A and licensing.

As we look to the future, we are sharply focused on developing new medicines in our chosen therapeutic areas that deliver value and progress for all impacted. We are also committed to working alongside governments and payers to deliver meaningful outcomes that help ease the long-term burden of these diseases for patients and all who support them on their journey.


  1. Global Genes Factsheet on Rare Diseases:
In this section

We have a history of doing things differently.


Taking an ethical and responsible approach to our business is part of what we do everyday.


Our leadership drives the Shire company vision.


Shire is committed to sound corporate governance principles, practices, and policies.


The opportunity to make breakthrough progress is what motivates us to come to work each day.


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