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    <title><![CDATA[Shire Plc - Shire News Feed]]></title>
    <link><![CDATA[http://www.shire.com]]></link>
    <description><![CDATA[Shire News Feed]]></description>
    <language><![CDATA[en-gb]]></language>
    <copyright><![CDATA[Copyright 2012 Shire Plc. All rights reserved.]]></copyright>
    <lastBuildDate><![CDATA[Wed, 01 Feb 2012 11:42:30 +0000]]></lastBuildDate>
    <pubDate>Wed, 01 Feb 2012 11:42:30 +0000</pubDate>
    <category><![CDATA[Feeds]]></category><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=557]]></link>    			 			
        <pubDate>01 Feb 2012 11:42:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=557]]></guid>
    </item><item>
        <title><![CDATA[Shire and Sangamo Collaborate to Develop Therapeutics for the Treatment of Hemophilia and Other Monogenic Diseases]]></title>	
        <description><![CDATA[Shire and Sangamo Collaborate to Develop Therapeutics for the Treatment of Hemophilia and Other Monogenic Diseases]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=556]]></link>    			 			
        <pubDate>01 Feb 2012 11:39:57 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=556]]></guid>
    </item><item>
        <title><![CDATA[Full Year 2011 results date notification – February 9, 2012]]></title>	
        <description><![CDATA[Full Year 2011 results date notification – February 9, 2012]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=555]]></link>    			 			
        <pubDate>31 Jan 2012 10:58:54 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=555]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=554]]></link>    			 			
        <pubDate>23 Jan 2012 11:44:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=554]]></guid>
    </item><item>
        <title><![CDATA[Shire Acquires US Rights to Resolor® (prucalopride)]]></title>	
        <description><![CDATA[Shire Acquires US Rights to Resolor® (prucalopride)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=553]]></link>    			 			
        <pubDate>10 Jan 2012 10:02:37 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=553]]></guid>
    </item><item>
        <title><![CDATA[Shire’s VENVANSE® (lisdexamfetamine dimesylate) Marketing Application accepted for review in Europe]]></title>	
        <description><![CDATA[Shire’s VENVANSE® (lisdexamfetamine dimesylate) Marketing Application accepted for review in Europe]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=552]]></link>    			 			
        <pubDate>05 Jan 2012 11:57:43 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=552]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=551]]></link>    			 			
        <pubDate>03 Jan 2012 11:51:57 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=551]]></guid>
    </item><item>
        <title><![CDATA[Share dealing by a Person Discharging Managerial Responsibility]]></title>	
        <description><![CDATA[Share dealing by a Person Discharging Managerial Responsibility]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=550]]></link>    			 			
        <pubDate>30 Dec 2011 09:47:22 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=550]]></guid>
    </item><item>
        <title><![CDATA[Shire plc Board and Committee Changes]]></title>	
        <description><![CDATA[Shire plc Board and Committee Changes]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=549]]></link>    			 			
        <pubDate>15 Dec 2011 02:17:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=549]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=548]]></link>    			 			
        <pubDate>14 Dec 2011 10:01:56 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=548]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=547]]></link>    			 			
        <pubDate>12 Dec 2011 04:14:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=547]]></guid>
    </item><item>
        <title><![CDATA[Shire Reports Positive Phase II Results for Investigative Use of Vyvanse® (lisdexamfetamine dimesylate) Capsules, (CII)]]></title>	
        <description><![CDATA[Shire Reports Positive Phase II Results for Investigative Use of Vyvanse® (lisdexamfetamine dimesylate) Capsules, (CII)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=546]]></link>    			 			
        <pubDate>08 Dec 2011 03:59:14 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=546]]></guid>
    </item><item>
        <title><![CDATA[ProAmatine® Update: Path Forward Agreed]]></title>	
        <description><![CDATA[ProAmatine® Update: Path Forward Agreed]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=545]]></link>    			 			
        <pubDate>02 Dec 2011 06:18:14 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=545]]></guid>
    </item><item>
        <title><![CDATA[ADDERALL® (mixed salts of a single-entity amphetamine product) Supply Clarification]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=544]]></link>    			 			
        <pubDate>01 Dec 2011 04:38:15 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=544]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=542]]></link>    			 			
        <pubDate>01 Dec 2011 12:07:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=542]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=541]]></link>    			 			
        <pubDate>01 Dec 2011 12:02:04 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=541]]></guid>
    </item><item>
        <title><![CDATA[Block listing six monthly return]]></title>	
        <description><![CDATA[Block listing six monthly return]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=540]]></link>    			 			
        <pubDate>24 Nov 2011 12:04:28 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=540]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces Regulatory Filings in US and EU for New Manufacturing Facility ]]></title>	
        <description><![CDATA[Shire Announces Regulatory Filings in US and EU for New Manufacturing Facility ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=539]]></link>    			 			
        <pubDate>22 Nov 2011 08:35:23 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=539]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=538]]></link>    			 			
        <pubDate>21 Nov 2011 04:18:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=538]]></guid>
    </item><item>
        <title><![CDATA[BRAVE Awards Recipients Announced]]></title>	
        <description><![CDATA[BRAVE Awards Recipients Announced]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=537]]></link>    			 			
        <pubDate>18 Nov 2011 05:26:17 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=537]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces Strategic Partnership for ADHD Medicines in Japan with Shionogi & Co., Ltd. ]]></title>	
        <description><![CDATA[Shire Announces Strategic Partnership for ADHD Medicines in Japan with Shionogi & Co., Ltd.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=536]]></link>    			 			
        <pubDate>18 Nov 2011 07:35:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=536]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=535]]></link>    			 			
        <pubDate>07 Nov 2011 11:51:11 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=535]]></guid>
    </item><item>
        <title><![CDATA[PDMR Share Transactions]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=534]]></link>    			 			
        <pubDate>02 Nov 2011 03:00:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=534]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=533]]></link>    			 			
        <pubDate>01 Nov 2011 11:25:10 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=533]]></guid>
    </item><item>
        <title><![CDATA[Director Declaration]]></title>	
        <description><![CDATA[Director Declaration]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=532]]></link>    			 			
        <pubDate>01 Nov 2011 10:07:21 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=532]]></guid>
    </item><item>
        <title><![CDATA[Continued strong product sales performance in Q3: On track to deliver significant 2011 earnings growth]]></title>	
        <description><![CDATA[Continued strong product sales performance in Q3: On track to deliver significant 2011 earnings growth]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=531]]></link>    			 			
        <pubDate>28 Oct 2011 11:00:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=531]]></guid>
    </item><item>
        <title><![CDATA[EU study shows once-daily lisdexamfetamine dimesylate (LDX) effective for symptom control in children and adolescents with ADHD]]></title>	
        <description><![CDATA[EU study shows once-daily lisdexamfetamine dimesylate (LDX) effective for symptom control in children and adolescents with ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=530]]></link>    			 			
        <pubDate>21 Oct 2011 12:02:07 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=530]]></guid>
    </item><item>
        <title><![CDATA[Bloomberg interview - Shire To Expand in Regenerative Medicine, CEO Says]]></title>	
        <description><![CDATA[Bloomberg interview - Shire To Expand in Regenerative Medicine, CEO Says]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=529]]></link>    			 			
        <pubDate>20 Oct 2011 10:19:12 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=529]]></guid>
    </item><item>
        <title><![CDATA[Shire Canada grants SickKids $200,000 to support paediatric research and ADHD]]></title>	
        <description><![CDATA[Shire Canada grants SickKids $200,000 to support paediatric research and ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=528]]></link>    			 			
        <pubDate>13 Oct 2011 12:15:44 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=528]]></guid>
    </item><item>
        <title><![CDATA[Third quarter 2011 results date notification – October 28, 2011]]></title>	
        <description><![CDATA[Third quarter 2011 results date notification – October 28, 2011]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=527]]></link>    			 			
        <pubDate>13 Oct 2011 07:33:37 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=527]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=526]]></link>    			 			
        <pubDate>03 Oct 2011 02:56:42 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=526]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=525]]></link>    			 			
        <pubDate>30 Sep 2011 04:37:43 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=525]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=524]]></link>    			 			
        <pubDate>26 Sep 2011 04:22:19 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=524]]></guid>
    </item><item>
        <title><![CDATA[Shire Provides Update on ProAmatine® (midodrine HCl)]]></title>	
        <description><![CDATA[Shire Provides Update on ProAmatine® (midodrine HCl)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=523]]></link>    			 			
        <pubDate>22 Sep 2011 04:57:38 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=523]]></guid>
    </item><item>
        <title><![CDATA[Elections for Interim Dividend in Respect of the Six Months to June 30, 2011]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=522]]></link>    			 			
        <pubDate>01 Sep 2011 03:54:33 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=522]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=521]]></link>    			 			
        <pubDate>01 Sep 2011 01:35:49 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=521]]></guid>
    </item><item>
        <title><![CDATA[FDA Approves Shire’s FIRAZYR® (icatibant injection) for Acute Attacks of Hereditary Angioedema (HAE)]]></title>	
        <description><![CDATA[FDA Approves Shire’s FIRAZYR® (icatibant injection) for Acute Attacks of Hereditary Angioedema (HAE)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=520]]></link>    			 			
        <pubDate>25 Aug 2011 09:57:10 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=520]]></guid>
    </item><item>
        <title><![CDATA[Top-Line Results from Pivotal Trial of Dermagraft® for Venous Leg Ulcers]]></title>	
        <description><![CDATA[Top-Line Results from Pivotal Trial of Dermagraft® for Venous Leg Ulcers]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=519]]></link>    			 			
        <pubDate>24 Aug 2011 03:10:43 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=519]]></guid>
    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=518]]></link>    			 			
        <pubDate>12 Aug 2011 12:40:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=518]]></guid>
    </item><item>
        <title><![CDATA[Half Yearly Report]]></title>	
        <description><![CDATA[Half Yearly Report]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=517]]></link>    			 			
        <pubDate>11 Aug 2011 03:24:04 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=517]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=516]]></link>    			 			
        <pubDate>03 Aug 2011 02:34:58 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=516]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding ]]></title>	
        <description><![CDATA[Director/PDMR Shareholding ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=515]]></link>    			 			
        <pubDate>02 Aug 2011 06:18:04 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=515]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding ]]></title>	
        <description><![CDATA[Director/PDMR Shareholding ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=514]]></link>    			 			
        <pubDate>01 Aug 2011 05:40:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=514]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=512]]></link>    			 			
        <pubDate>01 Aug 2011 10:26:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=512]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=511]]></link>    			 			
        <pubDate>29 Jul 2011 05:02:24 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=511]]></guid>
    </item><item>
        <title><![CDATA[Shire's quarterly revenues grow by 25% to $1 billion for the first time]]></title>	
        <description><![CDATA[Shire's quarterly revenues grow by 25% to $1 billion for the first time]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=510]]></link>    			 			
        <pubDate>28 Jul 2011 11:23:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=510]]></guid>
    </item><item>
        <title><![CDATA[Board Changes]]></title>	
        <description><![CDATA[Board Changes ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=509]]></link>    			 			
        <pubDate>27 Jul 2011 11:13:36 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=509]]></guid>
    </item><item>
        <title><![CDATA[Lialda® (Mesalamine) Now Approved in U.S. for Maintenance of Remission of Ulcerative Colitis]]></title>	
        <description><![CDATA[Lialda® (Mesalamine) Now Approved in U.S. for Maintenance of Remission of Ulcerative Colitis]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=507]]></link>    			 			
        <pubDate>18 Jul 2011 10:58:25 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=507]]></guid>
    </item><item>
        <title><![CDATA[Second quarter 2011 results date notification – July 28, 2011]]></title>	
        <description><![CDATA[Second quarter 2011 results date notification – July 28, 2011]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=506]]></link>    			 			
        <pubDate>15 Jul 2011 11:57:52 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=506]]></guid>
    </item><item>
        <title><![CDATA[Shire named “Business of the Year” at  2011 First Women Awards]]></title>	
        <description><![CDATA[Shire named “Business of the Year” at 2011 First Women Awards]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=508]]></link>    			 			
        <pubDate>08 Jul 2011 04:34:43 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=508]]></guid>
    </item><item>
        <title><![CDATA[Shire files lawsuits against Watson and Roxane for infringement of VYVANSE® (lisdexamfetamine dimesylate) patents]]></title>	
        <description><![CDATA[Shire files lawsuits against Watson and Roxane for infringement of VYVANSE® (lisdexamfetamine dimesylate) patents]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=505]]></link>    			 			
        <pubDate>07 Jul 2011 11:17:57 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=505]]></guid>
    </item><item>
        <title><![CDATA[Shire files lawsuits against Sandoz and Amneal for infringement of VYVANSE®]]></title>	
        <description><![CDATA[Shire files lawsuits against Sandoz and Amneal for infringement of VYVANSE® (lisdexamfetamine dimesylate) patents]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=504]]></link>    			 			
        <pubDate>01 Jul 2011 04:45:34 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=504]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=503]]></link>    			 			
        <pubDate>01 Jul 2011 12:08:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=503]]></guid>
    </item><item>
        <title><![CDATA[Shire completes acquisition of Advanced BioHealing, Inc.]]></title>	
        <description><![CDATA[Shire completes acquisition of Advanced BioHealing, Inc.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=502]]></link>    			 			
        <pubDate>28 Jun 2011 02:28:56 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=502]]></guid>
    </item><item>
        <title><![CDATA[Shire named "Company of the Year" at Mediscience Awards for second consecutive year]]></title>	
        <description><![CDATA[Shire named "Company of the Year" at Mediscience Awards for second consecutive year]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=501]]></link>    			 			
        <pubDate>27 Jun 2011 11:07:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=501]]></guid>
    </item><item>
        <title><![CDATA[European Authorities Approve New Manufacturing Facility for Shire’s REPLAGAL® (agalsidase alfa)]]></title>	
        <description><![CDATA[European Authorities Approve New Manufacturing Facility for Shire’s REPLAGAL® (agalsidase alfa)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=500]]></link>    			 			
        <pubDate>24 Jun 2011 02:23:54 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=500]]></guid>
    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=499]]></link>    			 			
        <pubDate>24 Jun 2011 01:43:21 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=499]]></guid>
    </item><item>
        <title><![CDATA[FDA Advisory Committee Strongly Recommends Approval and Self-Administration of FIRAZYR® (icatibant) for the Treatment of Acute Attacks of Hereditary Angioedema]]></title>	
        <description><![CDATA[FDA Advisory Committee Strongly Recommends Approval and Self-Administration of FIRAZYR® (icatibant) for the Treatment of Acute Attacks of Hereditary Angioedema]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=498]]></link>    			 			
        <pubDate>23 Jun 2011 10:47:35 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=498]]></guid>
    </item><item>
        <title><![CDATA[Shire Launches BRAVE Awards to Recognize Caregivers]]></title>	
        <description><![CDATA[Shire Launches BRAVE Awards to Recognize Caregivers]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=497]]></link>    			 			
        <pubDate>21 Jun 2011 04:05:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=497]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=496]]></link>    			 			
        <pubDate>21 Jun 2011 03:25:56 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=496]]></guid>
    </item><item>
        <title><![CDATA[Shire Launches First BRAVE Awards to Recognise Carers]]></title>	
        <description><![CDATA[New international program to recognise unsung heroes dedicated to helping others]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=495]]></link>    			 			
        <pubDate>21 Jun 2011 10:05:48 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=495]]></guid>
    </item><item>
        <title><![CDATA[Maroon 5 Lead Singer Adam Levine Raises Awareness of Attention-Deficit/Hyperactivity Disorder in Young Adults and Adults With &quot;Own It&quot;]]></title>	
        <description><![CDATA[Maroon 5 Lead Singer Adam Levine Raises Awareness of Attention-Deficit/Hyperactivity Disorder in Young Adults and Adults With &quot;Own It”]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=494]]></link>    			 			
        <pubDate>20 Jun 2011 04:27:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=494]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=493]]></link>    			 			
        <pubDate>17 Jun 2011 03:19:07 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=493]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces Judges Panel for New Scholarship Program for Students Diagnosed with ADHD]]></title>	
        <description><![CDATA[Shire Announces Judges Panel for New Scholarship Program for Students Diagnosed with ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=491]]></link>    			 			
        <pubDate>14 Jun 2011 06:13:18 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=491]]></guid>
    </item><item>
        <title><![CDATA[Health Canada grants MEZAVANT<sup>®</sup> new expanded indication for maintenance of remission of Ulcerative Colitis]]></title>	
        <description><![CDATA[Health Canada grants MEZAVANT® new expanded indication for maintenance of remission of Ulcerative Colitis]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=490]]></link>    			 			
        <pubDate>07 Jun 2011 10:00:31 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=490]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=489]]></link>    			 			
        <pubDate>01 Jun 2011 05:51:37 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=489]]></guid>
    </item><item>
        <title><![CDATA[First Results of European Survey Show Significant Impact Of ADHD At School And Home, Yet Parents Wait Over Two Years for An ADHD Diagnosis]]></title>	
        <description><![CDATA[First Results of European Survey Show Significant Impact Of ADHD At School And Home, Yet Parents Wait Over Two Years for An ADHD Diagnosis]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=488]]></link>    			 			
        <pubDate>28 May 2011 04:59:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=488]]></guid>
    </item><item>
        <title><![CDATA[Calling All Students Diagnosed with ADHD – There’s a Scholarship for You!]]></title>	
        <description><![CDATA[Calling All Students Diagnosed with ADHD – There’s a Scholarship for You!]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=487]]></link>    			 			
        <pubDate>25 May 2011 06:09:01 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=487]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives VYVANSE® Paragraph IV Notice Letters]]></title>	
        <description><![CDATA[Shire Receives VYVANSE® Paragraph IV Notice Letters]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=486]]></link>    			 			
        <pubDate>25 May 2011 10:38:24 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=486]]></guid>
    </item><item>
        <title><![CDATA[Block listing six monthly return]]></title>	
        <description><![CDATA[Block listing six monthly return]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=485]]></link>    			 			
        <pubDate>24 May 2011 05:02:03 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=485]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives VYVANSE® Paragraph IV Notice Letter]]></title>	
        <description><![CDATA[Shire Receives VYVANSE® Paragraph IV Notice Letter]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=484]]></link>    			 			
        <pubDate>19 May 2011 02:51:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=484]]></guid>
    </item><item>
        <title><![CDATA[Shire to establish new Regenerative Medicine business unit through cash acquisition of Advanced BioHealing, Inc., including US marketed DERMAGRAFT®]]></title>	
        <description><![CDATA[Shire to establish new Regenerative Medicine business unit through cash acquisition of Advanced BioHealing, Inc., including US marketed DERMAGRAFT®]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=483]]></link>    			 			
        <pubDate>17 May 2011 09:08:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=483]]></guid>
    </item><item>
        <title><![CDATA[Bloomberg interview with Angus Russell, CEO]]></title>	
        <description><![CDATA[Bloomberg interview with Angus Russell, CEO]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=482]]></link>    			 			
        <pubDate>12 May 2011 11:18:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=482]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=481]]></link>    			 			
        <pubDate>09 May 2011 05:35:28 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=481]]></guid>
    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=480]]></link>    			 			
        <pubDate>06 May 2011 11:44:23 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=480]]></guid>
    </item><item>
        <title><![CDATA[Director Declaration]]></title>	
        <description><![CDATA[Director Declaration]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=479]]></link>    			 			
        <pubDate>04 May 2011 03:10:52 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=479]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=478]]></link>    			 			
        <pubDate>03 May 2011 11:51:22 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=478]]></guid>
    </item><item>
        <title><![CDATA[Shire delivers a strong first quarter performance]]></title>	
        <description><![CDATA[Shire delivers a strong first quarter performance]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=475]]></link>    			 			
        <pubDate>28 Apr 2011 02:40:46 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=475]]></guid>
    </item><item>
        <title><![CDATA[Shire Reports Positive Results from Signal Finding Study of Investigative Use of Vyvanse® (lisdexamfetamine dimesylate) Capsules (CII) as Adjunctive Treatment in Predominant Negative Symptom Schizophrenia]]></title>	
        <description><![CDATA[Shire Reports Positive Results from Signal Finding Study of Investigative Use of Vyvanse® (lisdexamfetamine dimesylate) Capsules (CII) as Adjunctive Treatment in Predominant Negative Symptom Schizophrenia]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=477]]></link>    			 			
        <pubDate>28 Apr 2011 02:31:21 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=477]]></guid>
    </item><item>
        <title><![CDATA[Results of the Annual General Meeting]]></title>	
        <description><![CDATA[Results of the Annual General Meeting]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=470]]></link>    			 			
        <pubDate>26 Apr 2011 06:59:29 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=470]]></guid>
    </item><item>
        <title><![CDATA[First quarter 2011 results date notification – April 28, 2011]]></title>	
        <description><![CDATA[First quarter 2011 results date notification – April 28, 2011]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=469]]></link>    			 			
        <pubDate>21 Apr 2011 12:19:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=469]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares ]]></title>	
        <description><![CDATA[Notification of major interests in shares ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=468]]></link>    			 			
        <pubDate>19 Apr 2011 02:12:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=468]]></guid>
    </item><item>
        <title><![CDATA[Shire files lawsuit against Watson Pharmaceuticals, Inc. for infringement of ADDERALL XR® patents and for breach of contract.]]></title>	
        <description><![CDATA[Shire files lawsuit against Watson Pharmaceuticals, Inc. for infringement of ADDERALL XR® patents and for breach of contract.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=467]]></link>    			 			
        <pubDate>06 Apr 2011 06:50:58 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=467]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=466]]></link>    			 			
        <pubDate>01 Apr 2011 04:04:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=466]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=465]]></link>    			 			
        <pubDate>01 Apr 2011 02:15:59 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=465]]></guid>
    </item><item>
        <title><![CDATA[Annual Information Update]]></title>	
        <description><![CDATA[Annual Information Update]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=464]]></link>    			 			
        <pubDate>01 Apr 2011 11:23:44 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=464]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=463]]></link>    			 			
        <pubDate>29 Mar 2011 01:46:22 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=463]]></guid>
    </item><item>
        <title><![CDATA[2010 Annual Report – DTR 6.3.5 Disclosure]]></title>	
        <description><![CDATA[2010 Annual Report – DTR 6.3.5 Disclosure]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=462]]></link>    			 			
        <pubDate>24 Mar 2011 10:38:15 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=462]]></guid>
    </item><item>
        <title><![CDATA[FDA Assigns PDUFA Date for Shire’s FIRAZYR® (icatibant) for the Treatment of Acute Attacks of Hereditary Angioedema]]></title>	
        <description><![CDATA[FDA Assigns PDUFA Date for Shire’s FIRAZYR® (icatibant) for the Treatment of Acute Attacks of Hereditary Angioedema]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=460]]></link>    			 			
        <pubDate>21 Mar 2011 10:03:08 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=460]]></guid>
    </item><item>
        <title><![CDATA[Shire Presents Data at ACMG for Fabry and Gaucher Patients Who Switched to Replagal® (agalsidase alfa) and VPRIV® (velaglucerase alfa for injection)]]></title>	
        <description><![CDATA[Shire Presents Data at ACMG for Fabry and Gaucher Patients Who Switched to Replagal® (agalsidase alfa) and VPRIV®
(velaglucerase alfa for injection)
]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=459]]></link>    			 			
        <pubDate>21 Mar 2011 09:16:42 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=459]]></guid>
    </item><item>
        <title><![CDATA[European Commission Approves Self-Administration Label for FIRAZYR® (icatibant) for the Symptomatic Treatment of Acute Hereditary Angioedema Attacks]]></title>	
        <description><![CDATA[European Commission Approves Self-Administration Label for FIRAZYR® (icatibant) for the Symptomatic Treatment of Acute Hereditary Angioedema Attacks]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=458]]></link>    			 			
        <pubDate>03 Mar 2011 09:38:04 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=458]]></guid>
    </item><item>
        <title><![CDATA[Correction: Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Correction: Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=457]]></link>    			 			
        <pubDate>02 Mar 2011 11:54:35 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=457]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=456]]></link>    			 			
        <pubDate>01 Mar 2011 05:45:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=456]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=455]]></link>    			 			
        <pubDate>01 Mar 2011 11:55:25 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=455]]></guid>
    </item><item>
        <title><![CDATA[Elections for Interim Dividend in Respect of the Six Months to December 31, 2010]]></title>	
        <description><![CDATA[Elections for Interim Dividend in Respect of the Six Months to December 31, 2010]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=454]]></link>    			 			
        <pubDate>01 Mar 2011 11:05:33 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=454]]></guid>
    </item><item>
        <title><![CDATA[FDA Approves INTUNIV® (guanfacine) Extended-Release Tablets for Use as Adjunctive Therapy to Stimulants for the Treatment of ADHD in Children and Adolescents]]></title>	
        <description><![CDATA[FDA Approves INTUNIV® (guanfacine) Extended-Release Tablets for Use as Adjunctive Therapy to Stimulants for the Treatment of ADHD in Children and Adolescents ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=453]]></link>    			 			
        <pubDate>28 Feb 2011 11:06:25 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=453]]></guid>
    </item><item>
        <title><![CDATA[Shire Supports World Rare Disease Day 2011 ]]></title>	
        <description><![CDATA[Shire Supports World Rare Disease Day 2011 ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=452]]></link>    			 			
        <pubDate>28 Feb 2011 10:59:22 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=452]]></guid>
    </item><item>
        <title><![CDATA[Shire Files Complete Response to FDA’s Not Approvable Letter for FIRAZYR® (icatibant) for the Treatment of Acute Attacks of Hereditary Angioedema]]></title>	
        <description><![CDATA[Shire Files Complete Response to FDA’s Not Approvable Letter for FIRAZYR® (icatibant) for the Treatment of Acute Attacks of Hereditary Angioedema]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=451]]></link>    			 			
        <pubDate>28 Feb 2011 10:49:55 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=451]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives new Paragraph IV Notice Letter From Watson for ADDERALL XR®]]></title>	
        <description><![CDATA[Shire Receives new Paragraph IV Notice Letter From Watson for ADDERALL XR®]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=450]]></link>    			 			
        <pubDate>24 Feb 2011 03:43:17 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=450]]></guid>
    </item><item>
        <title><![CDATA[Outstanding 2010 results: Non GAAP EPS up 21% to $4.23. Good earnings growth expected in 2011.]]></title>	
        <description><![CDATA[Outstanding 2010 results: Non GAAP EPS up 21% to $4.23. Good earnings growth expected in 2011.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=449]]></link>    			 			
        <pubDate>10 Feb 2011 10:26:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=449]]></guid>
    </item><item>
        <title><![CDATA[Shire Strengthens Specialty Pharmaceuticals Team with Senior R&D Appointments]]></title>	
        <description><![CDATA[Shire Strengthens Specialty Pharmaceuticals Team with Senior R&D Appointments]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=447]]></link>    			 			
        <pubDate>08 Feb 2011 03:32:07 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=447]]></guid>
    </item><item>
        <title><![CDATA[Santé Canada approuve Vyvanse<sup>®</sup> pour le traitement du TDAH chez les adolescents et les adultes ]]></title>	
        <description><![CDATA[Santé Canada approuve Vyvanse® pour le traitement du TDAH chez les adolescents et les adultes ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=446]]></link>    			 			
        <pubDate>02 Feb 2011 06:55:06 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=446]]></guid>
    </item><item>
        <title><![CDATA[Health Canada Approves Vyvanse<sup>®</sup> for the Treatment of ADHD in Adolescents and Adults ]]></title>	
        <description><![CDATA[Health Canada Approves Vyvanse® for the Treatment of ADHD in Adolescents and Adults ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=445]]></link>    			 			
        <pubDate>02 Feb 2011 06:43:11 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=445]]></guid>
    </item><item>
        <title><![CDATA[Total voting Rights]]></title>	
        <description><![CDATA[Total voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=444]]></link>    			 			
        <pubDate>01 Feb 2011 02:12:06 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=444]]></guid>
    </item><item>
        <title><![CDATA[Full Year 2010 results date notification – February 10, 2011]]></title>	
        <description><![CDATA[Full Year 2010 results date notification – February 10, 2011]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=442]]></link>    			 			
        <pubDate>31 Jan 2011 04:02:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=442]]></guid>
    </item><item>
        <title><![CDATA[Shire Appoints New Head of European Government Relations and Public Policy]]></title>	
        <description><![CDATA[Shire Appoints New Head of European Government Relations and Public Policy]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=443]]></link>    			 			
        <pubDate>27 Jan 2011 11:14:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=443]]></guid>
    </item><item>
        <title><![CDATA[Shire Recognized by ISPE Facility of the Year Awards Program]]></title>	
        <description><![CDATA[Shire Recognized by ISPE Facility of the Year Awards Program]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=441]]></link>    			 			
        <pubDate>24 Jan 2011 09:29:56 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=441]]></guid>
    </item><item>
        <title><![CDATA[Shire Reports Positive Signal Finding Study of Investigative Use of Vyvanse<sup>®</sup> (lisdexamfetamine dimesylate) Capsules CII in Excessive Daytime Sleepiness Model]]></title>	
        <description><![CDATA[Shire Reports Positive Signal Finding Study of Investigative Use of Vyvanse® (lisdexamfetamine dimesylate) Capsules CII in Excessive Daytime Sleepiness Model]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=440]]></link>    			 			
        <pubDate>10 Jan 2011 01:52:39 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=440]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=436]]></link>    			 			
        <pubDate>04 Jan 2011 01:53:11 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=436]]></guid>
    </item><item>
        <title><![CDATA[INTUNIV™ - Shire Files Suit against Impax and Watson]]></title>	
        <description><![CDATA[INTUNIV™ - Shire Files Suit against Impax and Watson]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=435]]></link>    			 			
        <pubDate>03 Dec 2010 10:34:27 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=435]]></guid>
    </item><item>
        <title><![CDATA[VPRIV<sup>MC</sup> (vélaglucérase alfa) est approuvé au Canada pour le traitement de la maladie de Gaucher de type 1 ]]></title>	
        <description><![CDATA[VPRIVMC (vélaglucérase alfa) est approuvé au Canada pour le traitement de la maladie de Gaucher de type 1 ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=434]]></link>    			 			
        <pubDate>01 Dec 2010 02:37:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=434]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=433]]></link>    			 			
        <pubDate>01 Dec 2010 01:37:46 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=433]]></guid>
    </item><item>
        <title><![CDATA[Shire Reports Positive Efficacy and Safety Results From FAST-3 Study of FIRAZYR® (icatibant) for Acute Attacks of Hereditary Angioedema]]></title>	
        <description><![CDATA[Shire Reports Positive Efficacy and Safety Results From FAST-3 Study of FIRAZYR® (icatibant) for Acute Attacks of Hereditary Angioedema]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=431]]></link>    			 			
        <pubDate>01 Dec 2010 12:49:56 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=431]]></guid>
    </item><item>
        <title><![CDATA[VPRIV® (velaglucerase alfa) Approved in Canada for the Treatment of Type I Gaucher Disease]]></title>	
        <description><![CDATA[VPRIV® (velaglucerase alfa) Approved in Canada for the Treatment of Type I Gaucher Disease]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=432]]></link>    			 			
        <pubDate>01 Dec 2010 12:28:27 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=432]]></guid>
    </item><item>
        <title><![CDATA[Block listing six monthly return]]></title>	
        <description><![CDATA[Block listing six monthly return]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=430]]></link>    			 			
        <pubDate>23 Nov 2010 02:55:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=430]]></guid>
    </item><item>
        <title><![CDATA[FDA Approves Vyvanse<sup>®</sup> (lisdexamfetamine dimesylate) Capsules CII for the Treatment of ADHD in Adolescents]]></title>	
        <description><![CDATA[FDA Approves Vyvanse® (lisdexamfetamine dimesylate) Capsules CII for the Treatment of ADHD in Adolescents]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=448]]></link>    			 			
        <pubDate>15 Nov 2010 03:55:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=448]]></guid>
    </item><item>
        <title><![CDATA[Five-Year Market Exclusivity for VYVANSE® Upheld]]></title>	
        <description><![CDATA[Five-Year Market Exclusivity for VYVANSE® Upheld]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=428]]></link>    			 			
        <pubDate>10 Nov 2010 10:32:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=428]]></guid>
    </item><item>
        <title><![CDATA[Shire finalises its acquisition of Movetis NV following completion of the Squeeze-Out Process]]></title>	
        <description><![CDATA[Shire finalises its acquisition of Movetis NV following completion of the Squeeze-Out Process]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=427]]></link>    			 			
        <pubDate>09 Nov 2010 11:21:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=427]]></guid>
    </item><item>
        <title><![CDATA[Shire Presents Positive New Data at the 60th Annual American Society of Human Genetics (ASHG) for Patients with Type 1 Gaucher Disease]]></title>	
        <description><![CDATA[Head-to-Head Data Demonstrates Efficacy of VPRIV® (velaglucerase alfa for injection) Compared with Imiglucerase...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=426]]></link>    			 			
        <pubDate>04 Nov 2010 11:52:32 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=426]]></guid>
    </item><item>
        <title><![CDATA[Directors/PDMR Shareholding]]></title>	
        <description><![CDATA[Directors/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=425]]></link>    			 			
        <pubDate>02 Nov 2010 05:24:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=425]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=424]]></link>    			 			
        <pubDate>01 Nov 2010 01:36:40 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=424]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives INTUNIV™ Paragraph IV Notice Letter ]]></title>	
        <description><![CDATA[Shire Receives INTUNIV™ Paragraph IV Notice Letter ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=423]]></link>    			 			
        <pubDate>01 Nov 2010 07:57:22 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=423]]></guid>
    </item><item>
        <title><![CDATA[Continued excellent performance in Q3. Full year earnings expectations increased. New value in pipeline emerging]]></title>	
        <description><![CDATA[Continued excellent performance in Q3. Full year earnings expectations increased. New value in pipeline emerging]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=421]]></link>    			 			
        <pubDate>29 Oct 2010 10:33:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=421]]></guid>
    </item><item>
        <title><![CDATA[Shire Reports Positive Signal Finding Study of Investigative Use of Vyvanse® (lisdexamfetamine dimesylate) Capsules as Adjunctive Treatment in Major Depressive Disorder]]></title>	
        <description><![CDATA[Shire Reports Positive Signal Finding Study of Investigative Use of Vyvanse® (lisdexamfetamine dimesylate) Capsules as Adjunctive Treatment in Major Depressive Disorder]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=422]]></link>    			 			
        <pubDate>29 Oct 2010 10:25:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=422]]></guid>
    </item><item>
        <title><![CDATA[Investigational Data Presented for INTUNIV™ (guanfacine) Extended-Release Tablets When Coadministered With Stimulants Showed ADHD Symptom Improvement in Overall, Morning and Evening Assessments]]></title>	
        <description><![CDATA[Investigational Data Presented for INTUNIV™ (guanfacine) Extended-Release Tablets When Coadministered With Stimulants Showed ADHD Symptom Improvement in Overall, Morning and Evening Assessments]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=420]]></link>    			 			
        <pubDate>28 Oct 2010 04:51:01 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=420]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives INTUNIV™ Paragraph IV Notice Letter]]></title>	
        <description><![CDATA[Shire Receives INTUNIV™ Paragraph IV Notice Letter]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=419]]></link>    			 			
        <pubDate>26 Oct 2010 11:39:54 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=419]]></guid>
    </item><item>
        <title><![CDATA[Third quarter 2010 results date notification - October 29, 2010]]></title>	
        <description><![CDATA[Third quarter 2010 results date notification - October 29, 2010]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=418]]></link>    			 			
        <pubDate>18 Oct 2010 03:43:56 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=418]]></guid>
    </item><item>
        <title><![CDATA[Shire Acquires 99.21% of the shares of Movetis N.V. and Announces Commencement of Squeeze-Out Tender Period]]></title>	
        <description><![CDATA[Shire Acquires 99.21% of the shares of Movetis N.V. and Announces Commencement of Squeeze-Out Tender Period]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=417]]></link>    			 			
        <pubDate>13 Oct 2010 10:19:46 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=417]]></guid>
    </item><item>
        <title><![CDATA[Shire Appoints Philip J. Vickers, PhD as Senior Vice President of Research & Development for Human Genetic Therapies Business]]></title>	
        <description><![CDATA[Shire Appoints Philip J. Vickers, PhD as Senior Vice President of Research & Development for Human Genetic Therapies Business]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=416]]></link>    			 			
        <pubDate>11 Oct 2010 11:51:13 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=416]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=413]]></link>    			 			
        <pubDate>01 Oct 2010 03:59:10 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=413]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces Results of the Tender Offer for Movetis NV and Commencement of Squeeze-Out Tender Period]]></title>	
        <description><![CDATA[Shire Announces Results of the Tender Offer for Movetis NV and Commencement of Squeeze-Out Tender Period]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=412]]></link>    			 			
        <pubDate>30 Sep 2010 09:45:57 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=412]]></guid>
    </item><item>
        <title><![CDATA[“Fact or Fiction: ADHD in America, a Capitol Hill Forum” ]]></title>	
        <description><![CDATA[Briefing hosted by Shire, the Entertainment Industries Council and the Lab School of Washington with actress Roxy Olin delivering keynote on behalf of Entertainment Industries Council as part of its mental health advocacy tour]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=411]]></link>    			 			
        <pubDate>16 Sep 2010 11:42:10 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=411]]></guid>
    </item><item>
        <title><![CDATA[Shire Update on ProAmatine® (midodrine HCl)]]></title>	
        <description><![CDATA[Shire Update on ProAmatine® (midodrine HCl)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=410]]></link>    			 			
        <pubDate>13 Sep 2010 09:26:13 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=410]]></guid>
    </item><item>
        <title><![CDATA[Shire Expands Pipeline to Treat Orphan Muscle Diseases through Collaboration with Acceleron Pharma]]></title>	
        <description><![CDATA[Deal Grants Shire Exclusive Ex-North American Rights to Acceleron’s Innovative Class of ActRIIB Molecules, including ACE-031 Currently in Phase 2 Development to Treat Duchenne Muscular Dystrophy]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=409]]></link>    			 			
        <pubDate>09 Sep 2010 12:01:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=409]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces Commencement of Tender Offer to Acquire Movetis NV]]></title>	
        <description><![CDATA[Shire Announces Commencement of Tender Offer to Acquire Movetis NV]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=408]]></link>    			 			
        <pubDate>06 Sep 2010 06:15:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=408]]></guid>
    </item><item>
        <title><![CDATA[Elections for Interim Dividend in Respect of the Six Months to June 30, 2010]]></title>	
        <description><![CDATA[Elections for Interim Dividend in Respect of the Six Months to June 30, 2010]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=407]]></link>    			 			
        <pubDate>01 Sep 2010 03:35:37 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=407]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=406]]></link>    			 			
        <pubDate>01 Sep 2010 03:22:15 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=406]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces Support for Inflammatory Bowel Disease (IBD) Fellowships at Leading Medical Institutions Nationwide]]></title>	
        <description><![CDATA[Shire Announces Support for Inflammatory Bowel Disease (IBD) Fellowships at Leading Medical Institutions Nationwide]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=405]]></link>    			 			
        <pubDate>31 Aug 2010 03:49:07 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=405]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces European Approval of VPRIV<sup>®</sup> (velaglucerase alfa) for the Treatment of Type 1 Gaucher Disease]]></title>	
        <description><![CDATA[Shire Announces European Approval of VPRIV® (velaglucerase alfa) for the Treatment of Type 1 Gaucher Disease]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=404]]></link>    			 			
        <pubDate>26 Aug 2010 04:11:56 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=404]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=403]]></link>    			 			
        <pubDate>26 Aug 2010 03:29:32 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=403]]></guid>
    </item><item>
        <title><![CDATA[Pentasa<sup>®</sup> - Shire Receives Ruling From FDA on Citizen’s Petition]]></title>	
        <description><![CDATA[Pentasa® - Shire Receives Ruling From FDA on Citizen’s Petition]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=402]]></link>    			 			
        <pubDate>24 Aug 2010 04:40:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=402]]></guid>
    </item><item>
        <title><![CDATA[Correction - Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Correction - Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=401]]></link>    			 			
        <pubDate>20 Aug 2010 04:09:27 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=401]]></guid>
    </item><item>
        <title><![CDATA[Statement re ProAmatine]]></title>	
        <description><![CDATA[Statement re ProAmatine]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=400]]></link>    			 			
        <pubDate>17 Aug 2010 07:00:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=400]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=399]]></link>    			 			
        <pubDate>17 Aug 2010 04:15:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=399]]></guid>
    </item><item>
        <title><![CDATA[Half Yearly Report]]></title>	
        <description><![CDATA[Half Yearly Report]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=398]]></link>    			 			
        <pubDate>11 Aug 2010 11:41:35 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=398]]></guid>
    </item><item>
        <title><![CDATA[Shire agrees to divest Daytrana® (methylphenidate transdermal system) CII to Noven Pharmaceuticals, Inc.; Shire’s 2010 earnings outlook unchanged]]></title>	
        <description><![CDATA[Shire agrees to divest Daytrana® (methylphenidate
transdermal system) CII to Noven Pharmaceuticals, Inc.;Shire’s 2010 earnings outlook unchanged]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=397]]></link>    			 			
        <pubDate>10 Aug 2010 09:08:29 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=397]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=396]]></link>    			 			
        <pubDate>05 Aug 2010 04:42:58 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=396]]></guid>
    </item><item>
        <title><![CDATA[Published Study Demonstrated Once-Daily Vyvanse® (lisdexamfetamine dimesylate) Capsules CII Provided Significant Efficacy at Two Hours Through 14 Hours After Administration in Adults with ADHD]]></title>	
        <description><![CDATA[Published Study Demonstrated Once-Daily Vyvanse® (lisdexamfetamine dimesylate) Capsules CII Provided Significant Efficacy at Two Hours Through 14 Hours After Administration in Adults with ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=395]]></link>    			 			
        <pubDate>05 Aug 2010 04:00:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=395]]></guid>
    </item><item>
        <title><![CDATA[Study Published in the New England Journal of Medicine Demonstrates Efficacy and Favourable Safety Profile of Firazyr® (Icatibant) for the Treatment of Hereditary Angioedema (HAE) Attacks]]></title>	
        <description><![CDATA[Study Published in the New England Journal of Medicine Demonstrates Efficacy and Favourable Safety Profile of Firazyr® (Icatibant) for the Treatment of Hereditary Angioedema (HAE) Attacks]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=394]]></link>    			 			
        <pubDate>04 Aug 2010 04:35:28 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=394]]></guid>
    </item><item>
        <title><![CDATA[Shire delivers excellent Q2 performance with total revenues up 35%. Full year earnings expectations raised.]]></title>	
        <description><![CDATA[Shire delivers excellent Q2 performance with total revenues up 35%. Full year earnings expectations raised.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=393]]></link>    			 			
        <pubDate>04 Aug 2010 11:49:10 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=393]]></guid>
    </item><item>
        <title><![CDATA[Shire Proposes to Expand Specialist Gastrointestinal Portfolio]]></title>	
        <description><![CDATA[Shire Proposes to Expand Specialist Gastrointestinal Portfolio]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=392]]></link>    			 			
        <pubDate>03 Aug 2010 12:10:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=392]]></guid>
    </item><item>
        <title><![CDATA[Shire Appoints Gráinne Higgins Global Vice President of Human Resources for Human Genetic Therapies Business ]]></title>	
        <description><![CDATA[Shire Appoints Gráinne Higgins Global Vice President of Human Resources for Human Genetic Therapies Business ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=391]]></link>    			 			
        <pubDate>02 Aug 2010 05:56:46 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=391]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=390]]></link>    			 			
        <pubDate>02 Aug 2010 01:07:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=390]]></guid>
    </item><item>
        <title><![CDATA[Nonsafety voluntary recall and withdrawal of a limited portion of Daytrana® (methylphenidate transdermal system) patches]]></title>	
        <description><![CDATA[Nonsafety voluntary recall and withdrawal of a limited portion of Daytrana® (methylphenidate transdermal system) patches]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=389]]></link>    			 			
        <pubDate>20 Jul 2010 07:01:41 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=389]]></guid>
    </item><item>
        <title><![CDATA[Second quarter 2010 results date notification – August 4, 2010]]></title>	
        <description><![CDATA[Second quarter 2010 results date notification – August 4, 2010]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=388]]></link>    			 			
        <pubDate>15 Jul 2010 11:23:54 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=388]]></guid>
    </item><item>
        <title><![CDATA[Lialda<sup>®</sup> - Shire Files Suit against Cadila Healthcare Limited, doing business as Zydus Cadila and Zydus Pharmaceuticals (USA), Inc.]]></title>	
        <description><![CDATA[Lialda® - Shire Files Suit against Cadila Healthcare Limited, doing business as Zydus Cadila and Zydus Pharmaceuticals ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=387]]></link>    			 			
        <pubDate>08 Jul 2010 06:55:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=387]]></guid>
    </item><item>
        <title><![CDATA[FDA Approves Daytrana® (methylphenidate transdermal system) CII for the Treatment of ADHD in Adolescents]]></title>	
        <description><![CDATA[FDA Approves Daytrana® (methylphenidate transdermal system) CII for the Treatment of ADHD in Adolescents]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=382]]></link>    			 			
        <pubDate>06 Jul 2010 02:19:08 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=382]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=380]]></link>    			 			
        <pubDate>01 Jul 2010 05:37:33 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=380]]></guid>
    </item><item>
        <title><![CDATA[Data Presented at the European Working Group on Gaucher Disease Demonstrate Continuous Improvements in Bone Mineral Density for VPRIV® (velaglucerase alfa) through 69 months]]></title>	
        <description><![CDATA[Data Presented at the European Working Group on Gaucher Disease Demonstrate Continuous Improvements in Bone Mineral Density for VPRIV® (velaglucerase alfa) through 69 months]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=381]]></link>    			 			
        <pubDate>01 Jul 2010 02:17:13 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=381]]></guid>
    </item><item>
        <title><![CDATA[Shire Purchases Strategic Site in Massachusetts]]></title>	
        <description><![CDATA[Shire Purchases Strategic Site in Massachusetts Transaction Allows Company to Continue its Growth]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=375]]></link>    			 			
        <pubDate>30 Jun 2010 05:04:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=375]]></guid>
    </item><item>
        <title><![CDATA[Shire named Company of the Year at Mediscience Awards]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company was named Company of the Year in the European Mediscience Awards 2010...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=374]]></link>    			 			
        <pubDate>28 Jun 2010 12:09:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=374]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives CHMP Positive Opinion for VPRIV™ (velaglucerase alfa) for the Treatment of Type 1 Gaucher Disease in the European Union]]></title>	
        <description><![CDATA[Shire plc announced today that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency adopted a positive opinion on the marketing...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=373]]></link>    			 			
        <pubDate>25 Jun 2010 01:40:04 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=373]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=372]]></link>    			 			
        <pubDate>21 Jun 2010 03:53:34 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=372]]></guid>
    </item><item>
        <title><![CDATA[Two New Board Directors Appointed]]></title>	
        <description><![CDATA[Non-Executives to join Shire’s Science & Technology and Remuneration Committees...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=371]]></link>    			 			
        <pubDate>17 Jun 2010 10:28:28 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=371]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives LIALDA® Paragraph IV Notice Letter from Zydus Pharmaceuticals]]></title>	
        <description><![CDATA[Shire plc announces that it has received a Paragraph IV Notice Letter today from Zydus Pharmaceuticals USA, Inc. (“Zydus”) advising of the filing of an Abbreviated New Drug Application...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=376]]></link>    			 			
        <pubDate>28 May 2010 08:08:22 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=376]]></guid>
    </item><item>
        <title><![CDATA[Study Evaluated Vyvanse<sup>®</sup> (lisdexamfetamine dimesylate) Capsules CII Efficacy and Safety in Adolescents with ADHD]]></title>	
        <description><![CDATA[Study Evaluated Vyvanse® (lisdexamfetamine dimesylate) Capsules CII Efficacy and Safety in Adolescents with ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=377]]></link>    			 			
        <pubDate>25 May 2010 06:29:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=377]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives 2010 Corporate Award from the National Organization for Rare Disorders (NORD) for the Development of VPRIV (velaglucerase alfa for injection) ]]></title>	
        <description><![CDATA[Organization Recognizes Shire’s Commitment to the Gaucher Disease Community...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=379]]></link>    			 			
        <pubDate>19 May 2010 01:22:36 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=379]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=366]]></link>    			 			
        <pubDate>04 May 2010 05:05:52 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=366]]></guid>
    </item><item>
        <title><![CDATA[FDA Approves Labeling Change for Vyvanse® (lisdexamfetamine dimesylate) Capsules CII to Include Supplemental Data Demonstrating Significant Efficacy at Two Hours Through 14 Hours After Administration in Adults with ADHD<sup>1</sup>]]></title>	
        <description><![CDATA[First Oral Long-Acting ADHD Stimulant Treatment To Have Efficacy Data for Adults at 14-hours Postdose in Product Labeling <sup>1-4</sup>]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=365]]></link>    			 			
        <pubDate>04 May 2010 05:03:24 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=365]]></guid>
    </item><item>
        <title><![CDATA[Shire's replenished portfolio drives excellent quarterly performance]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY) the global specialty biopharmaceutical company, announces results for the three months to March 31, 2010.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=362]]></link>    			 			
        <pubDate>29 Apr 2010 03:43:38 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=362]]></guid>
    </item><item>
        <title><![CDATA[Results of the Annual General Meeting held on April 27, 2010]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=364]]></link>    			 			
        <pubDate>27 Apr 2010 03:56:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=364]]></guid>
    </item><item>
        <title><![CDATA[First quarter 2010 results date notification – April 29, 2010]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=360]]></link>    			 			
        <pubDate>20 Apr 2010 10:11:12 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=360]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=358]]></link>    			 			
        <pubDate>01 Apr 2010 03:56:04 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=358]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=357]]></link>    			 			
        <pubDate>01 Apr 2010 03:33:25 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=357]]></guid>
    </item><item>
        <title><![CDATA[Annual Information Update]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=356]]></link>    			 			
        <pubDate>01 Apr 2010 03:26:34 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=356]]></guid>
    </item><item>
        <title><![CDATA[Annual Report and Accounts]]></title>	
        <description><![CDATA[In compliance with Listing Rule 9.6.1, Shire plc has submitted to the UK Listing Authority two copies of the Company’s Notice of the 2010...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=355]]></link>    			 			
        <pubDate>25 Mar 2010 04:48:27 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=355]]></guid>
    </item><item>
        <title><![CDATA[Shire Presents Positive Data for Patients with Type 1 Gaucher Disease Who Switched to VPRIV<sup>TM</sup>]]></title>	
        <description><![CDATA[Shire Presents Positive Data for Patients with Type 1 Gaucher Disease Who Switched to VPRIV(TM)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=354]]></link>    			 			
        <pubDate>25 Mar 2010 10:36:54 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=354]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=352]]></link>    			 			
        <pubDate>18 Mar 2010 02:50:08 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=352]]></guid>
    </item><item>
        <title><![CDATA[New Board Director Appointed]]></title>	
        <description><![CDATA[New Board Director Appointed]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=350]]></link>    			 			
        <pubDate>15 Mar 2010 01:42:24 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=350]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=349]]></link>    			 			
        <pubDate>11 Mar 2010 02:56:55 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=349]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=348]]></link>    			 			
        <pubDate>09 Mar 2010 02:53:41 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=348]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=342]]></link>    			 			
        <pubDate>05 Mar 2010 04:10:58 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=342]]></guid>
    </item><item>
        <title><![CDATA[District Court Upholds FDA’s Grant of 5-Year Market Exclusivity to VYVANSE®]]></title>	
        <description><![CDATA[District Court Upholds FDA’s Grant of 5-Year Market Exclusivity to VYVANSE®]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=341]]></link>    			 			
        <pubDate>04 Mar 2010 06:02:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=341]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=339]]></link>    			 			
        <pubDate>03 Mar 2010 06:55:29 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=339]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=340]]></link>    			 			
        <pubDate>03 Mar 2010 04:14:36 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=340]]></guid>
    </item><item>
        <title><![CDATA[Supplementary Reporting Announcement]]></title>	
        <description><![CDATA[Supplementary Reporting Announcement]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=338]]></link>    			 			
        <pubDate>02 Mar 2010 03:13:11 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=338]]></guid>
    </item><item>
        <title><![CDATA[Elections for Interim Dividend in Respect of the Six Months to December 31, 2009]]></title>	
        <description><![CDATA[Elections for Interim Dividend in Respect of the Six Months to December 31, 2009]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=335]]></link>    			 			
        <pubDate>01 Mar 2010 03:52:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=335]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=334]]></link>    			 			
        <pubDate>01 Mar 2010 12:08:14 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=334]]></guid>
    </item><item>
        <title><![CDATA[March is Kidney Health Month]]></title>	
        <description><![CDATA[Educating and Empowering Canadians to Prevent and Manage Kidney Disease]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=337]]></link>    			 			
        <pubDate>01 Mar 2010 10:59:46 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=337]]></guid>
    </item><item>
        <title><![CDATA[Mars est le mois de la santé rénale]]></title>	
        <description><![CDATA[Éduquer et outiller les Canadiens en matière de prévention et de gestion des maladies rénales]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=336]]></link>    			 			
        <pubDate>01 Mar 2010 10:28:57 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=336]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces FDA Approval of VPRIV™ (velaglucerase alfa for injection) for the Treatment of Type 1 Gaucher Disease]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=331]]></link>    			 			
        <pubDate>26 Feb 2010 11:11:06 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=331]]></guid>
    </item><item>
        <title><![CDATA[FDA Press Release - FDA Approves Therapy to Treat Gaucher Disease]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=332]]></link>    			 			
        <pubDate>26 Feb 2010 10:57:11 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=332]]></guid>
    </item><item>
        <title><![CDATA[Shire Supports Rare Disease Day 2010 ]]></title>	
        <description><![CDATA[Shire Supports Rare Disease Day 2010 ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=330]]></link>    			 			
        <pubDate>26 Feb 2010 12:00:15 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=330]]></guid>
    </item><item>
        <title><![CDATA[Shire Provides Update on Biologics License Application (BLA) Filing for REPLAGAL® (agalsidase alfa) with the U.S. Food and Drug Administration (FDA)]]></title>	
        <description><![CDATA[Shire Provides Update on Biologics License Application (BLA) Filing for REPLAGAL® (agalsidase alfa) with the U.S. Food and Drug Administration (FDA)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=329]]></link>    			 			
        <pubDate>24 Feb 2010 11:14:01 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=329]]></guid>
    </item><item>
        <title><![CDATA[Excellent results in a transformational year for Shire; core product sales up 25%]]></title>	
        <description><![CDATA[Excellent results in a transformational year for Shire; core product sales up 25%]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=328]]></link>    			 			
        <pubDate>19 Feb 2010 11:37:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=328]]></guid>
    </item><item>
        <title><![CDATA[Shire Presents Positive Efficacy and Safety Data for velaglucerase alfa in Treatment of Naïve Patients with Type 1 Gaucher Disease]]></title>	
        <description><![CDATA[Shire Presents Positive Efficacy and Safety Data for velaglucerase alfa in Treatment of Naïve Patients with Type 1 Gaucher Disease]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=327]]></link>    			 			
        <pubDate>11 Feb 2010 11:46:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=327]]></guid>
    </item><item>
        <title><![CDATA[Full Year 2009 results date notification – 19 February 2010]]></title>	
        <description><![CDATA[Full Year 2009 results date notification – 19 February 2010]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=326]]></link>    			 			
        <pubDate>04 Feb 2010 12:00:38 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=326]]></guid>
    </item><item>
        <title><![CDATA[Shire to Present Important Study Findings for Gaucher Disease Treatment and GLD Development Program at the Lysosomal Disease Network (LDN) World Symposium]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=325]]></link>    			 			
        <pubDate>03 Feb 2010 11:51:44 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=325]]></guid>
    </item><item>
        <title><![CDATA[VYVANSE® — new ADHD treatment option — now available in Canada]]></title>	
        <description><![CDATA[VYVANSE® — new ADHD treatment option — now available in Canada]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=324]]></link>    			 			
        <pubDate>01 Feb 2010 12:09:12 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=324]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=333]]></link>    			 			
        <pubDate>01 Feb 2010 07:42:13 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=333]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=343]]></link>    			 			
        <pubDate>26 Jan 2010 06:26:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=343]]></guid>
    </item><item>
        <title><![CDATA[Directorate Change]]></title>	
        <description><![CDATA[Directorate Change]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=323]]></link>    			 			
        <pubDate>18 Jan 2010 11:40:48 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=323]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=322]]></link>    			 			
        <pubDate>04 Jan 2010 02:47:31 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=322]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=321]]></link>    			 			
        <pubDate>29 Dec 2009 02:35:54 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=321]]></guid>
    </item><item>
        <title><![CDATA[Dr Michael Rosenblatt to step down as non-executive director]]></title>	
        <description><![CDATA[Dr Michael Rosenblatt to step down as non-executive director]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=320]]></link>    			 			
        <pubDate>23 Dec 2009 04:39:14 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=320]]></guid>
    </item><item>
        <title><![CDATA[Shire Submits Biologics License Application (BLA) for REPLAGAL<sup>®</sup> with the U.S. Food and Drug Administration (FDA)]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced that it has submitted a BLA with the FDA for REPLAGAL(agalsidase alfa), its enzyme replacement therapy for Fabry disease. REPLAGAL first received marketing authorization in the European Union in 2001, and is approved for the treatment of Fabry disease in 45 countries.
]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=318]]></link>    			 			
        <pubDate>22 Dec 2009 01:50:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=318]]></guid>
    </item><item>
        <title><![CDATA[Shire Expands its Award-Winning ADHD Support Resource, ADHDSupport.com, by Launching an ADHD Twitter™ Page]]></title>	
        <description><![CDATA[Patients, families, caregivers, and educators who are impacted by ADHD can now receive updates about ADHD via Twitter at http://twitter.com/adhdsupport]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=319]]></link>    			 			
        <pubDate>21 Dec 2009 02:19:15 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=319]]></guid>
    </item><item>
        <title><![CDATA[Membership of Board Committees]]></title>	
        <description><![CDATA[Membership of Board Committees]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=346]]></link>    			 			
        <pubDate>16 Dec 2009 07:13:47 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=346]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=345]]></link>    			 			
        <pubDate>16 Dec 2009 07:11:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=345]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=344]]></link>    			 			
        <pubDate>14 Dec 2009 07:08:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=344]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=317]]></link>    			 			
        <pubDate>11 Dec 2009 04:48:31 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=317]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=316]]></link>    			 			
        <pubDate>07 Dec 2009 01:09:04 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=316]]></guid>
    </item><item>
        <title><![CDATA[Non-safety-related voluntary recall of a limited portion of Daytrana® (methylphenidate transdermal system) patches announced]]></title>	
        <description><![CDATA[Non-safety-related voluntary recall of a limited portion of Daytrana® (methylphenidate transdermal system) patches announced]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=315]]></link>    			 			
        <pubDate>04 Dec 2009 09:27:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=315]]></guid>
    </item><item>
        <title><![CDATA[Shire and Teva Settle Litigation Concerning Supply of ADDERALL XR Authorized Generic]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces that it has settled the litigation with Teva Pharmaceuticals USA, Inc...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=314]]></link>    			 			
        <pubDate>02 Dec 2009 12:50:15 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=314]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=347]]></link>    			 			
        <pubDate>01 Dec 2009 08:32:11 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=347]]></guid>
    </item><item>
        <title><![CDATA[Shire Submits European Marketing Authorization Application (MAA) for velaglucerase alfa for the Treatment of Type 1 Gaucher Disease]]></title>	
        <description><![CDATA[Committee for Medicinal Products for Human Use (CHMP) Grants Accelerated Assessment...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=313]]></link>    			 			
        <pubDate>24 Nov 2009 12:47:08 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=313]]></guid>
    </item><item>
        <title><![CDATA[Block listing six monthly return]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=312]]></link>    			 			
        <pubDate>23 Nov 2009 03:46:42 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=312]]></guid>
    </item><item>
        <title><![CDATA[PDMR Shareholding ]]></title>	
        <description><![CDATA[PDMR Shareholding ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=309]]></link>    			 			
        <pubDate>12 Nov 2009 03:03:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=309]]></guid>
    </item><item>
        <title><![CDATA[Shire Reports Findings From an Analysis Examining Emotional Lability in Children With ADHD Taking VYVANSE® (lisdexamfetamine dimesylate) Capsules CII]]></title>	
        <description><![CDATA[Shire plc, the global specialty biopharmaceutical company, announced findings from a post hoc analysis examining emotional lability from Phase 3 study data with VYVANSE®. In this study, VYVANSE demonstrated significant improvement in Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms as measured by the ADHD Rating Scale IV (ADHD-RS IV) and Connors' Parent Rating Scale-Revised Short (CPRS-RS) in children with ADHD aged 6 to 12 years.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=308]]></link>    			 			
        <pubDate>12 Nov 2009 03:01:13 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=308]]></guid>
    </item><item>
        <title><![CDATA[Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse® (lisdexamfetamine dimesylate) Capsules CII]]></title>	
        <description><![CDATA[FOCUS program offers customized tips, tools, and practical strategies for adults with ADHD taking Vyvanse designed to help them manage their day-to-day life]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=311]]></link>    			 			
        <pubDate>11 Nov 2009 08:32:49 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=311]]></guid>
    </item><item>
        <title><![CDATA[FDA Grants Priority Review for Shire’s velaglucerase alfa for Type 1 Gaucher Disease]]></title>	
        <description><![CDATA[Shire plc, the global specialty biopharmaceutical company, today announced that the United States Food and Drug Administration (FDA) has granted Priority Review for the New Drug Application (NDA) for velaglucerase alfa, the company’s enzyme replacement therapy in development for the treatment of Type 1 Gaucher disease...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=306]]></link>    			 			
        <pubDate>04 Nov 2009 02:45:32 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=306]]></guid>
    </item><item>
        <title><![CDATA[Directors/PDMR Shareholding]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=305]]></link>    			 			
        <pubDate>03 Nov 2009 02:43:18 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=305]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[At close of business on October 30, 2009, Shire plc's issued voting share capital consisted of 561,053,621 ordinary shares with a nominal value of 5 pence...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=304]]></link>    			 			
        <pubDate>02 Nov 2009 02:40:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=304]]></guid>
    </item><item>
        <title><![CDATA[New Shire Board member]]></title>	
        <description><![CDATA[The Board of Directors of Shire plc (LSE: SHP, NASDAQ: SHPGY) announces that Mr David Stout joined the Board as a Non Executive Director with effect from 31 October 2009...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=303]]></link>    			 			
        <pubDate>02 Nov 2009 02:37:46 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=303]]></guid>
    </item><item>
        <title><![CDATA[Shire Reports Tolerability and Clinical Effects Results of DAYTRANA® (methylphenidate transdermal system) from Study in Adolescents with ADHD]]></title>	
        <description><![CDATA[Shire today announced findings at a major medical meeting from a Phase IIIb study of the tolerability and effectiveness of DAYTRANA® (methylphenidate transdermal system) in adolescents aged 13 to 17 years diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD).  In addition, data regarding the pharmacokinetic profile of DAYTRANA in children and adolescents was also presented.  DAYTRANA, the first and only patch for the treatment of ADHD, is indicated for use in children aged 6 to 12 years with the disorder...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=302]]></link>    			 			
        <pubDate>30 Oct 2009 02:33:19 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=302]]></guid>
    </item><item>
        <title><![CDATA[Shire continues to deliver excellent growth from core products]]></title>	
        <description><![CDATA[Shire continues to deliver excellent growth from core products]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=301]]></link>    			 			
        <pubDate>30 Oct 2009 02:18:34 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=301]]></guid>
    </item><item>
        <title><![CDATA[Shire Secures European Wide Label Extension for FOSRENOL® in Chronic Kidney Disease]]></title>	
        <description><![CDATA[FOSRENOL® (lanthanum carbonate) now approved in the EU to treat hyperphosphataemia ≥1.78mmol/L in chronic kidney disease patients not on dialysis...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=298]]></link>    			 			
        <pubDate>28 Oct 2009 01:57:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=298]]></guid>
    </item><item>
        <title><![CDATA[FDA Determines VYVANSE® was Properly Granted Five-Year Market Exclusivity]]></title>	
        <description><![CDATA[the Food and Drug Administration (FDA), following a thorough administrative review of governing statutory and regulatory standards and public comments, has affirmed its prior decision to grant five-year New Chemical Entity (NCE) exclusivity to lisdexamfetamine dimesylate—currently marketed by Shire U.S. Inc. for the treatment of attention-deficit hyperactivity disorder under the name VYVANSE®...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=297]]></link>    			 			
        <pubDate>26 Oct 2009 05:02:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=297]]></guid>
    </item><item>
        <title><![CDATA[Third quarter 2009 results date notification – October 30, 2009]]></title>	
        <description><![CDATA[22 Oct 2009 - Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, will announce third quarter 2009 earnings on Friday October 30, 2009.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=295]]></link>    			 			
        <pubDate>22 Oct 2009 03:15:37 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=295]]></guid>
    </item><item>
        <title><![CDATA[Shire Targets Fourth Quarter Filing of BLA for REPLAGAL® for Fabry Disease with U.S. FDA ]]></title>	
        <description><![CDATA[Early access for Fabry patients available under treatment protocol and emergency IND]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=294]]></link>    			 			
        <pubDate>21 Oct 2009 02:30:12 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=294]]></guid>
    </item><item>
        <title><![CDATA[Shire voluntarily enables further access to HIV/AIDS medicines for Rwanda]]></title>	
        <description><![CDATA[19 Oct 2009 - Shire Canada Inc., a division of Shire plc, announced today its voluntary cooperation to enable further royalty-free access to HIV/AIDS medicines for Rwanda as part of ongoing collaborative efforts to improve health and save lives in the developing world.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=282]]></link>    			 			
        <pubDate>19 Oct 2009 01:37:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=282]]></guid>
    </item><item>
        <title><![CDATA[Holding(s) in Company]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=293]]></link>    			 			
        <pubDate>15 Oct 2009 02:28:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=293]]></guid>
    </item><item>
        <title><![CDATA[Shire and Sandoz Settle All Pending Litigation Concerning ADDERALL XR®]]></title>	
        <description><![CDATA[Philadelphia, PA – October 13, 2009 – Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces that it has settled all pending litigation with Sandoz, Inc. (“Sandoz”) in connection with Sandoz’s Abbreviated New Drug Application (“ANDA”) and its attempt to market generic versions of Shire’s ADDERALL XR® (mixed amphetamine salts) for the treatment of Attention Deficit Hyperactivity Disorder...
]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=292]]></link>    			 			
        <pubDate>13 Oct 2009 02:25:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=292]]></guid>
    </item><item>
        <title><![CDATA[Data from a head-to-head crossover study evaluating FOSRENOL® and sevelamer published today]]></title>	
        <description><![CDATA[Direct comparison of the two non-calcium phosphate binders gives new insights
into relative efficacy]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=291]]></link>    			 			
        <pubDate>07 Oct 2009 02:23:59 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=291]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=290]]></link>    			 			
        <pubDate>01 Oct 2009 02:22:52 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=290]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company (the “Company”), announces that on September 25, 2009, it was notified by Mr Matthew Emmens, Chairman of the Company, of the exercise, on September 24, 2009, of an option over 927,731 Shire ordinary shares of 5p (“Shares”) at an exercise price of £3.6825...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=289]]></link>    			 			
        <pubDate>25 Sep 2009 02:20:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=289]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=288]]></link>    			 			
        <pubDate>22 Sep 2009 02:19:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=288]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company (the “Company”), announces that on September 18, 2009, Ms Anita Graham, a Person Discharging Managerial Responsibility, exercised an option over 44,568 Shire ordinary shares of 5p (“Shares”) at an exercise price of £5.26.  Ms Graham chose to use a net settled cashless exercise facility run by the Company which resulted in a total of 22,576 Shares being allotted to her.  The option over the remaining 21,992 Shares lapsed.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=287]]></link>    			 			
        <pubDate>18 Sep 2009 02:17:47 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=287]]></guid>
    </item><item>
        <title><![CDATA[Celebrity dancer, Karina Smirnoff, speaks out for the first time on how ADHD has impacted her life]]></title>	
        <description><![CDATA[“Dancing with the Stars” performer discusses her struggle with ADHD to encourage other adults with ADHD to seek evaluation and appropriate treatment]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=286]]></link>    			 			
        <pubDate>16 Sep 2009 01:55:48 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=286]]></guid>
    </item><item>
        <title><![CDATA[Update on velaglucerase alfa]]></title>	
        <description><![CDATA[08 Sep 2009 - Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, is committed to doing everything possible to assist Gaucher patients and their physicians during the imiglucerase supply shortage. Shire is pleased to be able to provide velaglucerase alfa well over a year ahead of previously anticipated commercial launch world wide. 
]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=281]]></link>    			 			
        <pubDate>08 Sep 2009 03:52:49 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=281]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Shire plc, the global specialty biopharmaceutical company (the “Company”), announces that on September 3, 2009 it was notified by Mr Angus Russell, Chief Executive Officer of the Company, of a sale on the same day of 17,219 Shire plc ordinary shares of £0.05 each (“Shares”).  The Shares were sold at a price of £10.29 per Share...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=285]]></link>    			 			
        <pubDate>04 Sep 2009 01:53:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=285]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company (the “Company”), announces that on September 2, 2009, Ms Barbara Deptula, a Person Discharging Managerial Responsibility, exercised an option over 110,000 Shire ordinary shares...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=284]]></link>    			 			
        <pubDate>03 Sep 2009 01:49:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=284]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Shire plc, the global specialty biopharmaceutical company,  in accordance with DTR 5.6.1 of the FSA’s Disclosure and Transparency Rules, notifies the market of the following: At close of business on August 28, 2009, Shire plc's issued voting share capital consisted of 560,337,155 ordinary shares with a nominal value of 5 pence...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=221]]></link>    			 			
        <pubDate>01 Sep 2009 04:14:13 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=221]]></guid>
    </item><item>
        <title><![CDATA[Elections for interim dividend in respect of the six months to June 30, 2009]]></title>	
        <description><![CDATA[Shire plc, the global specialty biopharmaceutical company, announced on August 5, 2009 an interim dividend of  2.147 US cents per Ordinary share payable on October 8, 2009 to shareholders on the register of members at the close of business on September 11, 2009...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=220]]></link>    			 			
        <pubDate>01 Sep 2009 04:10:41 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=220]]></guid>
    </item><item>
        <title><![CDATA[Shire Completes Submission of NDA for velaglucerase alfa for Type 1 Gaucher disease and Reports Positive Results for Remaining Two Phase III Trials]]></title>	
        <description><![CDATA[Cambridge, Massachusetts, US – September 1, 2009 – Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today reported that it has completed its submission of a New Drug Application (NDA) for velaglucerase alfa, its enzyme replacement therapy in development for the treatment of Type 1 Gaucher disease, with the U.S. Food and Drug Administration (FDA). The Company also announced positive results from the final two Phase III studies of velaglucerase alfa, with both studies reaching all of their primary and secondary endpoints. ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=219]]></link>    			 			
        <pubDate>01 Sep 2009 04:08:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=219]]></guid>
    </item><item>
        <title><![CDATA[Shire Builds Competitive Position of its HGT Business through Research Collaboration with Santaris Pharma A/S on LNA Drug Platform]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces today that it has entered into a research-based collaboration with Santaris Pharma A/S, a leading player in RNA-based therapeutics, to develop its proprietary Locked Nucleic Acid (LNA) technology in a range of rare diseases...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=222]]></link>    			 			
        <pubDate>24 Aug 2009 04:17:24 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=222]]></guid>
    </item><item>
        <title><![CDATA[Half Yearly Report]]></title>	
        <description><![CDATA[In order to meet its obligations under the Disclosure Rules and Transparency Rules of the United Kingdom Financial Services Authority, Shire plc (“Shire” or the “Group”) (LSE: SHP, NASDAQ: SHPGY) is publishing today its Half Yearly Report for the six months ended June 30, 2009...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=223]]></link>    			 			
        <pubDate>21 Aug 2009 04:20:28 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=223]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=5]]></link>    			 			
        <pubDate>19 Aug 2009 03:41:19 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=5]]></guid>
    </item><item>
        <title><![CDATA[Shire Initiates Two Adult ADHD Outreach Programs]]></title>	
        <description><![CDATA[Shire Initiates Two Adult ADHD Outreach Programs. A Second Mobile Tour Screens Adults for ADHD and the ADHD Clinical Education (ACE) Program Provides In-office Physician Education. ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=3]]></link>    			 			
        <pubDate>17 Aug 2009 01:10:34 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=3]]></guid>
    </item><item>
        <title><![CDATA[Membership of Board Committees]]></title>	
        <description><![CDATA[Membership of Board Committees]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=1]]></link>    			 			
        <pubDate>07 Aug 2009 10:55:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=1]]></guid>
    </item><item>
        <title><![CDATA[Q2 results - Core portfolio of products delivers 20% sales growth]]></title>	
        <description><![CDATA[Q2 results - Core portfolio of products delivers 20% sales growth]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=4]]></link>    			 			
        <pubDate>05 Aug 2009 01:59:15 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=4]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=11]]></link>    			 			
        <pubDate>03 Aug 2009 03:57:40 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=11]]></guid>
    </item><item>
        <title><![CDATA[Shire Reports Positive Results from First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions with FDA]]></title>	
        <description><![CDATA[Shire Reports Positive Results from First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions with FDA]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=2]]></link>    			 			
        <pubDate>03 Aug 2009 11:29:38 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=2]]></guid>
    </item><item>
        <title><![CDATA[Study Published in Child and Adolescent Psychiatry and Mental Health Demonstrated Once-Daily Vyvanse® (lisdexamfetamine dimesylate) CII Provided Significant Improvement of ADHD Symptoms for Children at 13 Hours After Administration ]]></title>	
        <description><![CDATA[Vyvanse is the first oral ADHD stimulant with published data that demonstrated significant ADHD symptom improvement from 1.5 hours up to 13 hours after administration in children, from morning through homework and family time]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=225]]></link>    			 			
        <pubDate>22 Jul 2009 10:14:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=225]]></guid>
    </item><item>
        <title><![CDATA[Second quarter 2009 results date notification – August 5, 2009]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, will announce second quarter 2009 earnings on Wednesday August 5, 2009.

Results press release will be issued at: 12:00 BST / 07:00 EDT
Conference call time: 14:00 BST / 09:00 EDT]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=280]]></link>    			 			
        <pubDate>21 Jul 2009 03:43:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=280]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives Fast Track Designation for velaglucerase alfa for Gaucher Disease]]></title>	
        <description><![CDATA[Lexington, Massachusetts, US – July 16, 2009 – Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces it has received  Fast Track designation from the U.S. Food and Drug Administration (FDA) for velaglucerase alfa, its enzyme replacement therapy in development for the treatment of Type I Gaucher disease. Shire is working with the FDA to determine subsequent steps and timing for the filing of its NDA...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=279]]></link>    			 			
        <pubDate>16 Jul 2009 03:41:49 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=279]]></guid>
    </item><item>
        <title><![CDATA[Message from Sylvie Grégoire, President, Human Genetic Therapies regarding the MLD experimental drug]]></title>	
        <description><![CDATA[We appreciate and fully respect the seriousness of Mr. Massart’s situation and empathize with his family’s heartache. 

As we have explained to Mr. Massart several times since Shire acquired this development program, we are unable to produce enough of this experimental enzyme replacement therapy to provide it to any new patients outside of clinical trials....]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=278]]></link>    			 			
        <pubDate>16 Jul 2009 03:38:42 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=278]]></guid>
    </item><item>
        <title><![CDATA[Dr Jeffrey Leiden appointed to Vertex Board.]]></title>	
        <description><![CDATA[Shire announces that Dr Jeffrey Leiden has been appointed a non executive director of Vertex Pharmaceuticals Inc.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=277]]></link>    			 			
        <pubDate>08 Jul 2009 03:37:18 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=277]]></guid>
    </item><item>
        <title><![CDATA[Shire has filed a treatment protocol for velaglucerase alfa for Gaucher Disease]]></title>	
        <description><![CDATA[Lexington, Massachusetts, US – Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces that, at the request of the FDA, in view of a potential restriction on the availability of the current approved and marketed treatment for Gaucher Disease patients, it has filed a treatment protocol for velaglucerase alfa, its enzyme replacement therapy in development for the treatment of Gaucher Disease...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=276]]></link>    			 			
        <pubDate>06 Jul 2009 03:33:17 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=276]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=275]]></link>    			 			
        <pubDate>01 Jul 2009 03:30:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=275]]></guid>
    </item><item>
        <title><![CDATA[Study Showed VYVANSE® (lisdexamfetamine dimesylate) CII Provided Significant Efficacy at 14 Hours After Administration in Adults with ADHD in an Adult Simulated Workplace Environment]]></title>	
        <description><![CDATA[VYVANSE is the first stimulant to establish duration of efficacy from two hours up to 14 hours after administration in adults with ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=274]]></link>    			 			
        <pubDate>01 Jul 2009 03:26:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=274]]></guid>
    </item><item>
        <title><![CDATA[New Study in Women with Fabry Disease, Demonstrates Significant Benefits of Treatment with REPLAGAL® (agalsidase alfa) 0.2mg/kg on Kidney Function, Heart Function and Burden of Disease]]></title>	
        <description><![CDATA[Results from the largest and longest examination of enzyme replacement therapy (ERT) in female Fabry patients.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=273]]></link>    			 			
        <pubDate>16 Jun 2009 03:22:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=273]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=272]]></link>    			 			
        <pubDate>01 Jun 2009 03:19:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=272]]></guid>
    </item><item>
        <title><![CDATA[FDA Approves Labeling Change for VYVANSE® (lisdexamfetamine dimesylate) CII to Include Supplementary Clinical Data Supporting Efficacy at 13 Hours Postdose in Children Aged 6 to 12 with ADHD]]></title>	
        <description><![CDATA[FDA Approves Labeling Change for VYVANSE® (lisdexamfetamine dimesylate) CII to Include Supplementary Clinical Data Supporting Efficacy at 13 Hours Postdose in Children Aged 6 to 12 with ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=270]]></link>    			 			
        <pubDate>01 Jun 2009 03:13:55 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=270]]></guid>
    </item><item>
        <title><![CDATA[Block Listing Six Monthly Return]]></title>	
        <description><![CDATA[Block Listing Six Monthly Return]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=269]]></link>    			 			
        <pubDate>26 May 2009 10:51:13 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=269]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=268]]></link>    			 			
        <pubDate>22 May 2009 10:25:24 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=268]]></guid>
    </item><item>
        <title><![CDATA[New Study Evaluating the ADHD Medication VYVANSE® (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC® 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)]]></title>	
        <description><![CDATA[PHILADELPHIA – Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced results of a study showing that coadministration of the ADHD medication VYVANSE® (lisdexamfetamine dimesylate) CII with the proton pump inhibitor (PPI) Prilosec OTC® 40 mg (20 mg X 2), did not alter the median time it took for maximum plasma concentration of d-amphetamine to be reached in the subjects evaluated.  In the same study, coadministration of Prilosec OTC with ADDERALL XR resulted in a nearly 45 percent reduction in the median time to reach maximum plasma concentrations of amphetamine, the active medication.  Other pharmacokinetic parameters (maximum plasma concentration and area under curve) of active medication were not altered for either VYVANSE or ADDERALL XR when coadministered with Prilosec OTC.  This study, which is the first to evaluate the pharmacokinetics of VYVANSE and ADDERALL XR taken alone and with Prilosec OTC 40 mg, was recently presented at the International Congress on Clinical Pharmacy, co-sponsored by the American College of Clinical Pharmacy (ACCP), in Orlando, FL...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=267]]></link>    			 			
        <pubDate>22 May 2009 10:23:43 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=267]]></guid>
    </item><item>
        <title><![CDATA[Results from a European Caregiver Survey Highlight the Impact of Attention Deficit Hyperactivity Disorder (ADHD) on the Child and the Family ]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced results of a European survey that found a child’s Attention Deficit Hyperactivity Disorder (ADHD) symptoms at school were a key concern for parents, yet outside of school their child’s ADHD also had significant impact on parents’ personal time<sup>1</sup>...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=266]]></link>    			 			
        <pubDate>21 May 2009 10:22:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=266]]></guid>
    </item><item>
        <title><![CDATA[Shire to Present New Scientific Data on its ADHD Treatments at a National Scientific Meeting of Psychiatrists on May 18]]></title>	
        <description><![CDATA[Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced that it will present key scientific data on its Attention Deficit Hyperactivity Disorder (ADHD) treatments lisdexamfetamine dimesylate (CII) and investigational non-scheduled guanfacine extended release, at a national scientific meeting of psychiatrists to be held May 16 -21 in San Francisco, CA...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=263]]></link>    			 			
        <pubDate>15 May 2009 09:21:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=263]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=262]]></link>    			 			
        <pubDate>12 May 2009 02:40:14 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=262]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[At close of business on April 30, 2009, Shire plc's issued voting share capital consisted of 560,281,443 ordinary shares with a nominal value of 5 pence...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=260]]></link>    			 			
        <pubDate>01 May 2009 02:34:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=260]]></guid>
    </item><item>
        <title><![CDATA[Shire begins the year with a strong performance]]></title>	
        <description><![CDATA[Shire begins the year with a strong performance]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=259]]></link>    			 			
        <pubDate>30 Apr 2009 02:33:31 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=259]]></guid>
    </item><item>
        <title><![CDATA[Results of the Annual General Meeting held on April 28, 2009]]></title>	
        <description><![CDATA[Results of the Annual General Meeting held on April 28, 2009]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=258]]></link>    			 			
        <pubDate>28 Apr 2009 02:31:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=258]]></guid>
    </item><item>
        <title><![CDATA[First quarter 2009 results date notification – April 30, 2009]]></title>	
        <description><![CDATA[First quarter 2009 results date notification – April 30, 2009]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=257]]></link>    			 			
        <pubDate>20 Apr 2009 08:49:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=257]]></guid>
    </item><item>
        <title><![CDATA[Shire files lawsuit against Natco Pharma for infringement of FOSRENOL® (lanthanum carbonate) patents]]></title>	
        <description><![CDATA[Shire files lawsuit against Natco Pharma for infringement of FOSRENOL® (lanthanum carbonate) patents]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=256]]></link>    			 			
        <pubDate>02 Apr 2009 08:46:29 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=256]]></guid>
    </item><item>
        <title><![CDATA[Annual Information Update]]></title>	
        <description><![CDATA[Annual Information Update]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=255]]></link>    			 			
        <pubDate>01 Apr 2009 08:45:18 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=255]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=254]]></link>    			 			
        <pubDate>01 Apr 2009 08:31:42 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=254]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interest in shares]]></title>	
        <description><![CDATA[Notification of major interest in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=253]]></link>    			 			
        <pubDate>01 Apr 2009 08:28:57 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=253]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=252]]></link>    			 			
        <pubDate>01 Apr 2009 08:24:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=252]]></guid>
    </item><item>
        <title><![CDATA[Shire and GlaxoSmithKline enter agreement to co-promote VYVANSE® (lisdexamfetamine dimesylate) CII for the treatment of adults with ADHD]]></title>	
        <description><![CDATA[Co-promotion agreement will double the VYVANSE sales effort across the country]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=251]]></link>    			 			
        <pubDate>31 Mar 2009 02:46:25 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=251]]></guid>
    </item><item>
        <title><![CDATA[Publication of Shire plc's Annual Report 2008]]></title>	
        <description><![CDATA[March 25, 2009 - Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces that its Annual Report and Accounts in respect of the year ended December 31, 2008 has been published on its website...]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=250]]></link>    			 			
        <pubDate>25 Mar 2009 02:45:27 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=250]]></guid>
    </item><item>
        <title><![CDATA[Saving a playground, lifting a neighborhood]]></title>	
        <description><![CDATA[Shire’s $165,000 Project Playground gives Feltonville children a place to play; announces three-year, $100,000 funding commitment to Philadelphia Department of Recreation]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=249]]></link>    			 			
        <pubDate>21 Mar 2009 02:42:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=249]]></guid>
    </item><item>
        <title><![CDATA[Shire files lawsuit against Mylan for infringement of FOSRENOL® (lanthanum carbonate) patent]]></title>	
        <description><![CDATA[Shire files lawsuit against Mylan for infringement of FOSRENOL® (lanthanum carbonate) patent]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=248]]></link>    			 			
        <pubDate>20 Mar 2009 02:37:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=248]]></guid>
    </item><item>
        <title><![CDATA[Non-safety-related voluntary market withdrawal of a limited portion of DAYTRANA® (methylphenidate transdermal system) patches announced ]]></title>	
        <description><![CDATA[Non-safety-related voluntary market withdrawal of a limited portion of DAYTRANA® (methylphenidate transdermal system) patches announced ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=247]]></link>    			 			
        <pubDate>20 Mar 2009 02:33:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=247]]></guid>
    </item><item>
        <title><![CDATA[Holding(s) in Company ]]></title>	
        <description><![CDATA[Holding(s) in Company ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=246]]></link>    			 			
        <pubDate>19 Mar 2009 02:32:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=246]]></guid>
    </item><item>
        <title><![CDATA[Shire files lawsuit against Barr Laboratories for infringement of FOSRENOL® (lanthanum carbonate) patents]]></title>	
        <description><![CDATA[Shire files lawsuit against Barr Laboratories for infringement of FOSRENOL® (lanthanum carbonate) patents]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=245]]></link>    			 			
        <pubDate>16 Mar 2009 02:29:08 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=245]]></guid>
    </item><item>
        <title><![CDATA[Shire withdraws European Application for DAYTRANA™ (methylphenidate transdermal system) ]]></title>	
        <description><![CDATA[Shire withdraws European Application for DAYTRANA™ (methylphenidate transdermal system) ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=244]]></link>    			 			
        <pubDate>16 Mar 2009 10:08:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=244]]></guid>
    </item><item>
        <title><![CDATA[World Kidney Day press release]]></title>	
        <description><![CDATA[World Kidney Day press release]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=243]]></link>    			 			
        <pubDate>12 Mar 2009 10:04:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=243]]></guid>
    </item><item>
        <title><![CDATA[Holding(s) in Company ]]></title>	
        <description><![CDATA[Holding(s) in Company ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=242]]></link>    			 			
        <pubDate>12 Mar 2009 10:04:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=242]]></guid>
    </item><item>
        <title><![CDATA[Holding(s) in Company]]></title>	
        <description><![CDATA[Holding(s) in Company]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=241]]></link>    			 			
        <pubDate>09 Mar 2009 10:03:29 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=241]]></guid>
    </item><item>
        <title><![CDATA[Holding(s) in Company]]></title>	
        <description><![CDATA[Holding(s) in Company]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=240]]></link>    			 			
        <pubDate>05 Mar 2009 10:02:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=240]]></guid>
    </item><item>
        <title><![CDATA[Elections for interim dividend in respect of the six months to December 31, 2008]]></title>	
        <description><![CDATA[Elections for interim dividend in respect of the six months to December 31, 2008]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=239]]></link>    			 			
        <pubDate>02 Mar 2009 09:47:39 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=239]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=238]]></link>    			 			
        <pubDate>02 Mar 2009 09:39:21 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=238]]></guid>
    </item><item>
        <title><![CDATA[Shire HGT Announces Support for Rare Disease Day]]></title>	
        <description><![CDATA[Shire HGT Announces Support for Rare Disease Day]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=237]]></link>    			 			
        <pubDate>26 Feb 2009 09:36:44 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=237]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=236]]></link>    			 			
        <pubDate>23 Feb 2009 09:33:12 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=236]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=235]]></link>    			 			
        <pubDate>23 Feb 2009 09:19:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=235]]></guid>
    </item><item>
        <title><![CDATA[Shire to enter European ADHD market with the acquisition of EQUASYM® IR and XL]]></title>	
        <description><![CDATA[Shire to enter European ADHD market with the acquisition of EQUASYM® IR and XL]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=234]]></link>    			 			
        <pubDate>20 Feb 2009 09:15:32 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=234]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces Opening of Office in Japan]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=233]]></link>    			 			
        <pubDate>20 Feb 2009 09:12:27 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=233]]></guid>
    </item><item>
        <title><![CDATA[Shire delivers excellent growth for the year, with the new product portfolio achieving sales of $1 billion]]></title>	
        <description><![CDATA[Shire delivers excellent growth for the year, with the new product portfolio achieving sales of $1 billion]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=232]]></link>    			 			
        <pubDate>19 Feb 2009 09:07:28 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=232]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives FOSRENOL Paragraph IV Notice Letters from Barr Laboratories and Mylan]]></title>	
        <description><![CDATA[Shire Receives FOSRENOL Paragraph IV Notice Letters from Barr Laboratories and Mylan]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=231]]></link>    			 			
        <pubDate>09 Feb 2009 09:06:10 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=231]]></guid>
    </item><item>
        <title><![CDATA[Full Year 2008 results date notification – 19 February 2009]]></title>	
        <description><![CDATA[Full Year 2008 results date notification – 19 February 2009]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=230]]></link>    			 			
        <pubDate>09 Feb 2009 08:58:10 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=230]]></guid>
    </item><item>
        <title><![CDATA[Change to Director's details]]></title>	
        <description><![CDATA[Change to Director's details]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=229]]></link>    			 			
        <pubDate>05 Feb 2009 08:56:00 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=229]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=228]]></link>    			 			
        <pubDate>02 Feb 2009 08:54:31 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=228]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=226]]></link>    			 			
        <pubDate>05 Jan 2009 08:51:33 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=226]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=10]]></link>    			 			
        <pubDate>17 Dec 2008 03:56:10 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=10]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=217]]></link>    			 			
        <pubDate>01 Dec 2008 10:32:54 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=217]]></guid>
    </item><item>
        <title><![CDATA[Block Listing Six Monthly Return]]></title>	
        <description><![CDATA[Block Listing Six Monthly Return]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=216]]></link>    			 			
        <pubDate>25 Nov 2008 10:32:07 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=216]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=215]]></link>    			 			
        <pubDate>25 Nov 2008 10:31:25 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=215]]></guid>
    </item><item>
        <title><![CDATA[Investor seminar ]]></title>	
        <description><![CDATA[Investor seminar ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=6]]></link>    			 			
        <pubDate>18 Nov 2008 03:46:57 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=6]]></guid>
    </item><item>
        <title><![CDATA[Confirmation of HGT business day - 18th November 2008]]></title>	
        <description><![CDATA[Confirmation of HGT business day - 18th November 2008]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=7]]></link>    			 			
        <pubDate>12 Nov 2008 03:49:32 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=7]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=8]]></link>    			 			
        <pubDate>07 Nov 2008 03:51:03 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=8]]></guid>
    </item><item>
        <title><![CDATA[Shire successfully settles former TKT shareholder appraisal rights litigation]]></title>	
        <description><![CDATA[Shire successfully settles former TKT shareholder appraisal rights litigation]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=214]]></link>    			 			
        <pubDate>05 Nov 2008 10:30:25 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=214]]></guid>
    </item><item>
        <title><![CDATA[Directors/PDMR Shareholding]]></title>	
        <description><![CDATA[Directors/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=213]]></link>    			 			
        <pubDate>04 Nov 2008 10:27:03 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=213]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=212]]></link>    			 			
        <pubDate>03 Nov 2008 10:26:23 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=212]]></guid>
    </item><item>
        <title><![CDATA[Shire’s new product portfolio delivers strong quarterly performance]]></title>	
        <description><![CDATA[Shire’s new product portfolio delivers strong quarterly performance]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=211]]></link>    			 			
        <pubDate>29 Oct 2008 10:25:39 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=211]]></guid>
    </item><item>
        <title><![CDATA[Third quarter 2008 results date notification – 29 October 2008]]></title>	
        <description><![CDATA[Third quarter 2008 results date notification – 29 October 2008]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=210]]></link>    			 			
        <pubDate>15 Oct 2008 10:22:55 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=210]]></guid>
    </item><item>
        <title><![CDATA[CHANGE OF NAME TO SHIRE PLC]]></title>	
        <description><![CDATA[CHANGE OF NAME TO SHIRE PLC]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=209]]></link>    			 			
        <pubDate>01 Oct 2008 10:22:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=209]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=208]]></link>    			 			
        <pubDate>01 Oct 2008 10:21:32 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=208]]></guid>
    </item><item>
        <title><![CDATA[Correction - Results of the Annual General Meeting held on September 24, 2008]]></title>	
        <description><![CDATA[Correction - Results of the Annual General Meeting held on September 24, 2008]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=206]]></link>    			 			
        <pubDate>25 Sep 2008 10:20:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=206]]></guid>
    </item><item>
        <title><![CDATA[Results of the Annual General Meeting held on September 24, 2008]]></title>	
        <description><![CDATA[Results of the Annual General Meeting held on September 24, 2008]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=205]]></link>    			 			
        <pubDate>24 Sep 2008 10:19:17 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=205]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=204]]></link>    			 			
        <pubDate>23 Sep 2008 10:18:23 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=204]]></guid>
    </item><item>
        <title><![CDATA[Notification of Acquisition of American Depository Shares by Persons Discharging Managerial Responsibilities]]></title>	
        <description><![CDATA[Notification of Acquisition of American Depository Shares by Persons Discharging Managerial Responsibilities]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=203]]></link>    			 			
        <pubDate>12 Sep 2008 10:14:51 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=203]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=202]]></link>    			 			
        <pubDate>08 Sep 2008 10:14:07 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=202]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=200]]></link>    			 			
        <pubDate>01 Sep 2008 03:07:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=200]]></guid>
    </item><item>
        <title><![CDATA[Elections for interim dividend in respect of the half year for the six months ended June, 30 2008]]></title>	
        <description><![CDATA[Elections for interim dividend in respect of the half year for the six months ended June, 30 2008]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=199]]></link>    			 			
        <pubDate>01 Sep 2008 03:06:41 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=199]]></guid>
    </item><item>
        <title><![CDATA[Notification of Acquisition of American Depository Shares by Persons Discharging Managerial Responsibilities]]></title>	
        <description><![CDATA[Notification of Acquisition of American Depository Shares by Persons Discharging Managerial Responsibilities]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=207]]></link>    			 			
        <pubDate>01 Sep 2008 10:20:49 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=207]]></guid>
    </item><item>
        <title><![CDATA[Notice of the 2008 Annual General Meeting and Proxy Card]]></title>	
        <description><![CDATA[Notice of the 2008 Annual General Meeting and Proxy Card]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=198]]></link>    			 			
        <pubDate>22 Aug 2008 03:05:55 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=198]]></guid>
    </item><item>
        <title><![CDATA[SHIRE ANNOUNCES HOLDING OF 81% IN JERINI AG AND PUBLICATION OF OFFER DOCUMENT]]></title>	
        <description><![CDATA[SHIRE ANNOUNCES HOLDING OF 81% IN JERINI AG AND PUBLICATION OF OFFER DOCUMENT]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=197]]></link>    			 			
        <pubDate>13 Aug 2008 03:05:07 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=197]]></guid>
    </item><item>
        <title><![CDATA[Half Yearly Report ]]></title>	
        <description><![CDATA[Half Yearly Report ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=201]]></link>    			 			
        <pubDate>07 Aug 2008 10:09:39 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=201]]></guid>
    </item><item>
        <title><![CDATA[Notification of Acquisition of Shares by Director/Person Discharging Managerial Responsibilities]]></title>	
        <description><![CDATA[Notification of Acquisition of Shares by Director/Person Discharging Managerial Responsibilities]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=195]]></link>    			 			
        <pubDate>06 Aug 2008 02:54:19 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=195]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=194]]></link>    			 			
        <pubDate>06 Aug 2008 02:53:31 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=194]]></guid>
    </item><item>
        <title><![CDATA[Notification of Acquisition of American Depository Shares by a Director/Person Discharging Managerial Responsibilities]]></title>	
        <description><![CDATA[Notification of Acquisition of American Depository Shares by a Director/Person Discharging Managerial Responsibilities]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=193]]></link>    			 			
        <pubDate>04 Aug 2008 02:52:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=193]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=192]]></link>    			 			
        <pubDate>04 Aug 2008 02:50:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=192]]></guid>
    </item><item>
        <title><![CDATA[Notification of Acquisition of American Depository Shares by a Director/Person Discharging Managerial Responsibilities]]></title>	
        <description><![CDATA[Notification of Acquisition of American Depository Shares by a Director/Person Discharging Managerial Responsibilities]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=191]]></link>    			 			
        <pubDate>04 Aug 2008 02:49:43 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=191]]></guid>
    </item><item>
        <title><![CDATA[CNBC interview with Angus Russell following Shire's Q2 results 2008]]></title>	
        <description><![CDATA[CNBC interview with Angus Russell following Shire's Q2 results 2008]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=190]]></link>    			 			
        <pubDate>01 Aug 2008 02:48:14 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=190]]></guid>
    </item><item>
        <title><![CDATA[Shire delivers strong quarter: driven by $243m of new product sales (+164% YOY growth). Revenue guidance upgraded.]]></title>	
        <description><![CDATA[Shire delivers strong quarter: driven by $243m of new product sales (+164% YOY growth). Revenue guidance upgraded.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=189]]></link>    			 			
        <pubDate>31 Jul 2008 02:47:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=189]]></guid>
    </item><item>
        <title><![CDATA[Tatjana May appointed Chair of Shire’s Corporate Responsibility Committee]]></title>	
        <description><![CDATA[Tatjana May appointed Chair of Shire’s Corporate Responsibility Committee]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=188]]></link>    			 			
        <pubDate>30 Jul 2008 02:45:49 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=188]]></guid>
    </item><item>
        <title><![CDATA[Shire Appoints Dr. Jeffrey Jonas Senior Vice President, R&D, Specialty Pharmaceuticals]]></title>	
        <description><![CDATA[Shire Appoints Dr. Jeffrey Jonas Senior Vice President, R&D, Specialty Pharmaceuticals]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=187]]></link>    			 			
        <pubDate>23 Jul 2008 02:44:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=187]]></guid>
    </item><item>
        <title><![CDATA[Robin Buchanan to step down as non-executive director on completion of term of office]]></title>	
        <description><![CDATA[Robin Buchanan to step down as non-executive director on completion of term of office]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=186]]></link>    			 			
        <pubDate>21 Jul 2008 02:33:08 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=186]]></guid>
    </item><item>
        <title><![CDATA[Jerini Receives European Commission Approval for FIRAZYR® (Icatibant) in the Treatment of HAE]]></title>	
        <description><![CDATA[Jerini Receives European Commission Approval for FIRAZYR® (Icatibant) in the Treatment of HAE]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=185]]></link>    			 			
        <pubDate>15 Jul 2008 02:32:27 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=185]]></guid>
    </item><item>
        <title><![CDATA[Second quarter 2008 results date notification - 31 July 2008]]></title>	
        <description><![CDATA[Second quarter 2008 results date notification - 31 July 2008]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=184]]></link>    			 			
        <pubDate>04 Jul 2008 02:31:36 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=184]]></guid>
    </item><item>
        <title><![CDATA[Shire erweitert HGT-Portfolio mit neuem Orphan-Arznei-mittel – Einführung in der EU steht unmittelbar bevor]]></title>	
        <description><![CDATA[Shire erweitert HGT-Portfolio mit neuem Orphan-Arznei-mittel – Einführung in der EU steht unmittelbar bevor]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=183]]></link>    			 			
        <pubDate>03 Jul 2008 02:30:18 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=183]]></guid>
    </item><item>
        <title><![CDATA[Shire to add new orphan drug to its HGT portfolio – EU launch imminent]]></title>	
        <description><![CDATA[Shire to add new orphan drug to its HGT portfolio – EU launch imminent]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=182]]></link>    			 			
        <pubDate>03 Jul 2008 02:28:48 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=182]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=181]]></link>    			 			
        <pubDate>19 Jun 2008 02:27:01 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=181]]></guid>
    </item><item>
        <title><![CDATA[Notification of Acquisition of American Depository Shares by Person Discharging Managerial Responsibilities]]></title>	
        <description><![CDATA[Notification of Acquisition of American Depository Shares by Person Discharging Managerial Responsibilities]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=180]]></link>    			 			
        <pubDate>16 Jun 2008 02:26:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=180]]></guid>
    </item><item>
        <title><![CDATA[Graham Hetherington appointed Chief Financial Officer and Board Director at Shire]]></title>	
        <description><![CDATA[Graham Hetherington appointed Chief Financial Officer and Board Director at Shire]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=179]]></link>    			 			
        <pubDate>10 Jun 2008 02:24:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=179]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces Approval of ELAPRASE® (idursulfase) in Brazil ]]></title>	
        <description><![CDATA[Shire Announces Approval of ELAPRASE® (idursulfase) in Brazil ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=178]]></link>    			 			
        <pubDate>27 May 2008 02:21:46 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=178]]></guid>
    </item><item>
        <title><![CDATA[Application for Listing of Shire Limited Ordinary Shares]]></title>	
        <description><![CDATA[Application for Listing of Shire Limited Ordinary Shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=177]]></link>    			 			
        <pubDate>23 May 2008 02:20:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=177]]></guid>
    </item><item>
        <title><![CDATA[Court Approves Scheme of Arrangement]]></title>	
        <description><![CDATA[Court Approves Scheme of Arrangement]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=176]]></link>    			 			
        <pubDate>22 May 2008 02:19:29 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=176]]></guid>
    </item><item>
        <title><![CDATA[Annual Information Update]]></title>	
        <description><![CDATA[Annual Information Update]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=175]]></link>    			 			
        <pubDate>20 May 2008 02:06:58 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=175]]></guid>
    </item><item>
        <title><![CDATA[Results of Court Meeting and Extraordinary General Meeting - Shareholders Approve Scheme of Arrangement and New Share Plans]]></title>	
        <description><![CDATA[Results of Court Meeting and Extraordinary General Meeting - Shareholders Approve Scheme of Arrangement and New Share Plans]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=174]]></link>    			 			
        <pubDate>09 May 2008 02:04:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=174]]></guid>
    </item><item>
        <title><![CDATA[Shire opens new office in Norway]]></title>	
        <description><![CDATA[Shire opens new office in Norway]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=173]]></link>    			 			
        <pubDate>09 May 2008 01:58:23 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=173]]></guid>
    </item><item>
        <title><![CDATA[Shire welcomes the Court of Appeal's decision that NICE review of Alzheimer's drugs was procedurally unfair]]></title>	
        <description><![CDATA[Shire welcomes the Court of Appeal's decision that NICE review of Alzheimer's drugs was procedurally unfair]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=172]]></link>    			 			
        <pubDate>01 May 2008 01:56:55 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=172]]></guid>
    </item><item>
        <title><![CDATA[Publication of Supplementary Prospectus]]></title>	
        <description><![CDATA[Publication of Supplementary Prospectus]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=171]]></link>    			 			
        <pubDate>28 Apr 2008 01:51:18 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=171]]></guid>
    </item><item>
        <title><![CDATA[Following a good start to the year Shire reaffirms full year 2008 financial guidance]]></title>	
        <description><![CDATA[Following a good start to the year Shire reaffirms full year 2008 financial guidance]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=170]]></link>    			 			
        <pubDate>25 Apr 2008 01:44:49 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=170]]></guid>
    </item><item>
        <title><![CDATA[Dr Michael Rosenblatt appointed Non-Executive Director at Shire]]></title>	
        <description><![CDATA[Dr Michael Rosenblatt appointed Non-Executive Director at Shire]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=169]]></link>    			 			
        <pubDate>24 Apr 2008 01:43:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=169]]></guid>
    </item><item>
        <title><![CDATA[Shire enhances its orphan drug pipeline with the acquisition of a new clinical candidate for Metachromatic Leukodystrophy]]></title>	
        <description><![CDATA[Shire enhances its orphan drug pipeline with the acquisition of a new clinical candidate for Metachromatic Leukodystrophy]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=168]]></link>    			 			
        <pubDate>24 Apr 2008 01:43:06 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=168]]></guid>
    </item><item>
        <title><![CDATA[FDA Approves VYVANSE (TM) (lisdexamfetamine dimesylate), the First and Only Once-Daily Prodrug Stimulant to Treat ADHD in Adults]]></title>	
        <description><![CDATA[FDA Approves VYVANSE (TM) (lisdexamfetamine dimesylate), the First and Only Once-Daily Prodrug Stimulant to Treat ADHD in Adults]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=167]]></link>    			 			
        <pubDate>23 Apr 2008 01:41:33 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=167]]></guid>
    </item><item>
        <title><![CDATA[New Shire Holding Company Proposal]]></title>	
        <description><![CDATA[New Shire Holding Company Proposal]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=166]]></link>    			 			
        <pubDate>16 Apr 2008 01:40:07 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=166]]></guid>
    </item><item>
        <title><![CDATA[First Quarter 2008 Results Date Notification]]></title>	
        <description><![CDATA[First Quarter 2008 Results Date Notification]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=165]]></link>    			 			
        <pubDate>16 Apr 2008 01:35:28 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=165]]></guid>
    </item><item>
        <title><![CDATA[SHIRE TO INTRODUCE A NEW UK LISTED HOLDING COMPANY]]></title>	
        <description><![CDATA[SHIRE TO INTRODUCE A NEW UK LISTED HOLDING COMPANY]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=164]]></link>    			 			
        <pubDate>15 Apr 2008 01:34:41 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=164]]></guid>
    </item><item>
        <title><![CDATA[Annual Report and Accounts for the year ended December 31, 2007]]></title>	
        <description><![CDATA[Annual Report and Accounts for the year ended December 31, 2007]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=163]]></link>    			 			
        <pubDate>04 Apr 2008 01:33:54 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=163]]></guid>
    </item><item>
        <title><![CDATA[Movement of shares out of the Employee Benefit Trust ]]></title>	
        <description><![CDATA[Movement of shares out of the Employee Benefit Trust ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=162]]></link>    			 			
        <pubDate>02 Apr 2008 01:33:03 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=162]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=161]]></link>    			 			
        <pubDate>31 Mar 2008 01:32:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=161]]></guid>
    </item><item>
        <title><![CDATA[IFRS results for the year ending December 31, 2007 ]]></title>	
        <description><![CDATA[]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=159]]></link>    			 			
        <pubDate>25 Mar 2008 01:05:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=159]]></guid>
    </item><item>
        <title><![CDATA[RENOVO ANNNOUNCES JUVISTA® PHASE 2 TRIAL RESULTS IN SCAR REVISION AND BREAST AUGMENTATION SURGERY ]]></title>	
        <description><![CDATA[RENOVO ANNNOUNCES JUVISTA® PHASE 2 TRIAL RESULTS IN SCAR REVISION AND BREAST AUGMENTATION SURGERY ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=158]]></link>    			 			
        <pubDate>03 Mar 2008 01:04:13 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=158]]></guid>
    </item><item>
        <title><![CDATA[Renovo announces results of latest Phase 2 studies of JUVISTA(R) (human recombinant TGF Beta 3)]]></title>	
        <description><![CDATA[Renovo announces results of latest Phase 2 studies of JUVISTA(R) (human recombinant TGF Beta 3)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=157]]></link>    			 			
        <pubDate>03 Mar 2008 01:01:14 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=157]]></guid>
    </item><item>
        <title><![CDATA[Growing Support for World Kidney Day]]></title>	
        <description><![CDATA[Growing Support for World Kidney Day]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=156]]></link>    			 			
        <pubDate>27 Feb 2008 01:00:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=156]]></guid>
    </item><item>
        <title><![CDATA[Notification of Acquisition of American Depository Shares by Persons Discharging Managerial Responsibilities]]></title>	
        <description><![CDATA[Notification of Acquisition of American Depository Shares by Persons Discharging Managerial Responsibilities]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=155]]></link>    			 			
        <pubDate>26 Feb 2008 12:59:21 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=155]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding ]]></title>	
        <description><![CDATA[Director/PDMR Shareholding ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=154]]></link>    			 			
        <pubDate>25 Feb 2008 12:58:41 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=154]]></guid>
    </item><item>
        <title><![CDATA[CNBC interview with Matthew Emmens, CEO, following Shire’s full year 2007 results (video)]]></title>	
        <description><![CDATA[CNBC interview with Matthew Emmens, CEO, following Shire’s full year 2007 results (video)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=153]]></link>    			 			
        <pubDate>21 Feb 2008 12:57:19 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=153]]></guid>
    </item><item>
        <title><![CDATA[Q4, YEAR 2007 RESULTS]]></title>	
        <description><![CDATA[Q4, YEAR 2007 RESULTS]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=152]]></link>    			 			
        <pubDate>21 Feb 2008 12:56:28 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=152]]></guid>
    </item><item>
        <title><![CDATA[Correction]]></title>	
        <description><![CDATA[Correction]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=151]]></link>    			 			
        <pubDate>20 Feb 2008 12:55:49 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=151]]></guid>
    </item><item>
        <title><![CDATA[Healthcare Businesswomen’s Association Announces 2008 Woman of the Year, Charlotte Sibley, Senior Vice President, Leadership Development, Shire Pharmaceuticals]]></title>	
        <description><![CDATA[Healthcare Businesswomen’s Association Announces 2008 Woman of the Year, Charlotte Sibley, Senior Vice President, Leadership Development, Shire Pharmaceuticals]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=150]]></link>    			 			
        <pubDate>19 Feb 2008 12:54:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=150]]></guid>
    </item><item>
        <title><![CDATA[Shire HGT Announces Commitment to Continue Expansion in Massachusetts ]]></title>	
        <description><![CDATA[Shire HGT Announces Commitment to Continue Expansion in Massachusetts ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=149]]></link>    			 			
        <pubDate>14 Feb 2008 12:54:04 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=149]]></guid>
    </item><item>
        <title><![CDATA[Shire’s ELAPRASE® (idursulfase) Approved in Mexico for Treatment of Hunter Syndrome]]></title>	
        <description><![CDATA[Shire’s ELAPRASE® (idursulfase) Approved in Mexico for Treatment of Hunter Syndrome]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=148]]></link>    			 			
        <pubDate>13 Feb 2008 12:53:27 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=148]]></guid>
    </item><item>
        <title><![CDATA[Full Year 2007 results date notification – 21 February 2008]]></title>	
        <description><![CDATA[Full Year 2007 results date notification – 21 February 2008]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=147]]></link>    			 			
        <pubDate>12 Feb 2008 12:52:08 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=147]]></guid>
    </item><item>
        <title><![CDATA[Shire Completes Fosrenol® Roll-Out in Major European Markets With Launch in Spain]]></title>	
        <description><![CDATA[Shire Completes Fosrenol® Roll-Out in Major European Markets With Launch in Spain]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=146]]></link>    			 			
        <pubDate>17 Jan 2008 12:51:23 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=146]]></guid>
    </item><item>
        <title><![CDATA[Shire expands its gastrointestinal portfolio through in-licensing Celiac disease Phase 2 product from Alba Therapeutics Corporation]]></title>	
        <description><![CDATA[Shire expands its gastrointestinal portfolio through in-licensing Celiac disease Phase 2 product from Alba Therapeutics Corporation]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=145]]></link>    			 			
        <pubDate>14 Dec 2007 12:50:34 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=145]]></guid>
    </item><item>
        <title><![CDATA[Board Changes]]></title>	
        <description><![CDATA[Board Changes]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=144]]></link>    			 			
        <pubDate>13 Dec 2007 12:49:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=144]]></guid>
    </item><item>
        <title><![CDATA[Permission granted to challenge the High Court ruling to restrict Alzheimers’ drugs access on the NHS]]></title>	
        <description><![CDATA[Permission granted to challenge the High Court ruling to restrict Alzheimers’ drugs access on the NHS]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=143]]></link>    			 			
        <pubDate>06 Dec 2007 12:48:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=143]]></guid>
    </item><item>
        <title><![CDATA[Shire Pharmaceuticals donates over 400 laptops ]]></title>	
        <description><![CDATA[Shire Pharmaceuticals donates over 400 laptops ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=142]]></link>    			 			
        <pubDate>27 Nov 2007 12:47:29 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=142]]></guid>
    </item><item>
        <title><![CDATA[Shire Human Genetic Therapies Appoints Dr. Whaijen Soo to Manage the R&D of its Expanding Treatment Portfolio]]></title>	
        <description><![CDATA[Shire Human Genetic Therapies Appoints Dr. Whaijen Soo to Manage the R&D of its Expanding Treatment Portfolio]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=141]]></link>    			 			
        <pubDate>20 Nov 2007 12:45:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=141]]></guid>
    </item><item>
        <title><![CDATA[Shire pleased with Vyvanse growth - Reuters Health Summit (video)]]></title>	
        <description><![CDATA[Shire pleased with Vyvanse growth - Reuters Health Summit (video)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=140]]></link>    			 			
        <pubDate>13 Nov 2007 12:44:09 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=140]]></guid>
    </item><item>
        <title><![CDATA[Shire expands its Human Genetic Therapies pipeline through in-licensing agreement with Amicus Therapeutics]]></title>	
        <description><![CDATA[Shire expands its Human Genetic Therapies pipeline through in-licensing agreement with Amicus Therapeutics]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=139]]></link>    			 			
        <pubDate>08 Nov 2007 12:43:21 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=139]]></guid>
    </item><item>
        <title><![CDATA[New non-clinical data links DYNEPO® (epoetin delta) to Reduced Angiogenic Potential ]]></title>	
        <description><![CDATA[New non-clinical data links DYNEPO® (epoetin delta) to Reduced Angiogenic Potential ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=138]]></link>    			 			
        <pubDate>05 Nov 2007 12:42:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=138]]></guid>
    </item><item>
        <title><![CDATA[Further upgrade to 2007 financial guidance based on strong revenue growth; VYVANSE™ demand on track]]></title>	
        <description><![CDATA[Further upgrade to 2007 financial guidance based on strong revenue growth; VYVANSE™ demand on track]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=137]]></link>    			 			
        <pubDate>01 Nov 2007 12:41:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=137]]></guid>
    </item><item>
        <title><![CDATA[David Mott appointed Non Executive Director at Shire]]></title>	
        <description><![CDATA[David Mott appointed Non Executive Director at Shire]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=136]]></link>    			 			
        <pubDate>31 Oct 2007 12:18:34 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=136]]></guid>
    </item><item>
        <title><![CDATA[Shire launches clinical study results website]]></title>	
        <description><![CDATA[Shire launches clinical study results website]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=135]]></link>    			 			
        <pubDate>25 Oct 2007 12:14:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=135]]></guid>
    </item><item>
        <title><![CDATA[Third quarter 2007 results date notification]]></title>	
        <description><![CDATA[Third quarter 2007 results date notification]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=134]]></link>    			 			
        <pubDate>17 Oct 2007 12:10:43 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=134]]></guid>
    </item><item>
        <title><![CDATA[Reinforcing strategic focus on growth-driving global products]]></title>	
        <description><![CDATA[Reinforcing strategic focus on growth-driving global products]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=133]]></link>    			 			
        <pubDate>08 Oct 2007 12:07:01 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=133]]></guid>
    </item><item>
        <title><![CDATA[Shire’s ELAPRASE® (idursulfase) Approved in Japan For the Treatment of Hunter Syndrome]]></title>	
        <description><![CDATA[Shire’s ELAPRASE® (idursulfase) Approved in Japan For the Treatment of Hunter Syndrome]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=132]]></link>    			 			
        <pubDate>04 Oct 2007 12:05:12 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=132]]></guid>
    </item><item>
        <title><![CDATA[Shire to support appeal against outcome of Judicial Review of NICE guidance which denies newly diagnosed patients with mild Alzheimer's disease access to drugs on the NHS]]></title>	
        <description><![CDATA[Shire to support appeal against outcome of Judicial Review of NICE guidance which denies newly diagnosed patients with mild Alzheimer's disease access to drugs on the NHS]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=131]]></link>    			 			
        <pubDate>01 Oct 2007 11:27:42 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=131]]></guid>
    </item><item>
        <title><![CDATA[Families Invited to Celebrate "Shire Day" at Boston Children’s Museum]]></title>	
        <description><![CDATA[Families Invited to Celebrate "Shire Day" at Boston Children’s Museum]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=130]]></link>    			 			
        <pubDate>28 Sep 2007 11:25:40 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=130]]></guid>
    </item><item>
        <title><![CDATA[Shire launches Clinical Study Results Database]]></title>	
        <description><![CDATA[Shire launches Clinical Study Results Database]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=129]]></link>    			 			
        <pubDate>28 Sep 2007 11:24:31 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=129]]></guid>
    </item><item>
        <title><![CDATA[Shire Appoints Sylvie Gregoire President of Human Genetic Therapies Business]]></title>	
        <description><![CDATA[Shire Appoints Sylvie Gregoire President of Human Genetic Therapies Business]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=128]]></link>    			 			
        <pubDate>24 Sep 2007 11:23:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=128]]></guid>
    </item><item>
        <title><![CDATA[IFRS Information – First half of 2007]]></title>	
        <description><![CDATA[IFRS Information – First half of 2007]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=127]]></link>    			 			
        <pubDate>13 Sep 2007 11:22:58 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=127]]></guid>
    </item><item>
        <title><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a Director/PDMR.]]></title>	
        <description><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a Director/PDMR.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=126]]></link>    			 			
        <pubDate>12 Sep 2007 11:20:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=126]]></guid>
    </item><item>
        <title><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a PDMR.]]></title>	
        <description><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a PDMR.]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=125]]></link>    			 			
        <pubDate>12 Sep 2007 11:19:59 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=125]]></guid>
    </item><item>
        <title><![CDATA[Statistically significant efficacy of Juvista® demonstrated in phase 2 trial using drug substance manufactured by Lonza Biologics]]></title>	
        <description><![CDATA[Statistically significant efficacy of Juvista® demonstrated in phase 2 trial using drug substance manufactured by Lonza Biologics]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=124]]></link>    			 			
        <pubDate>12 Sep 2007 11:18:49 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=124]]></guid>
    </item><item>
        <title><![CDATA[Revised NICE Guidance on Alzheimer's disease (AD) confirms reliance on the MMSE<sup>1</sup>  for majority of patients and continued exclusion from NHS treatment for those with mild AD]]></title>	
        <description><![CDATA[Revised NICE Guidance on Alzheimer's disease (AD) confirms reliance on the MMSE<sup>1</sup>  for majority of patients and continued exclusion from NHS treatment for those with mild AD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=123]]></link>    			 			
        <pubDate>07 Sep 2007 11:17:48 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=123]]></guid>
    </item><item>
        <title><![CDATA[New partnership promises bright future for organic chemistry in the UK]]></title>	
        <description><![CDATA[New partnership promises bright future for organic chemistry in the UK]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=122]]></link>    			 			
        <pubDate>05 Sep 2007 11:16:08 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=122]]></guid>
    </item><item>
        <title><![CDATA[Shire voluntarily withdraws a limited portion of DAYTRANA™ (methylphenidate transdermal system) patches]]></title>	
        <description><![CDATA[Shire voluntarily withdraws a limited portion of DAYTRANA™ (methylphenidate transdermal system) patches]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=121]]></link>    			 			
        <pubDate>04 Sep 2007 11:15:18 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=121]]></guid>
    </item><item>
        <title><![CDATA[Shire supports Canada's Access to Medicines Regime]]></title>	
        <description><![CDATA[Shire supports Canada's Access to Medicines Regime]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=120]]></link>    			 			
        <pubDate>15 Aug 2007 11:14:39 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=120]]></guid>
    </item><item>
        <title><![CDATA[Expiry of Hart-Scott-Rodino waiting period for JUVISTA® (human TGFβ3)]]></title>	
        <description><![CDATA[Expiry of Hart-Scott-Rodino waiting period for JUVISTA® (human TGFβ3)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=119]]></link>    			 			
        <pubDate>15 Aug 2007 11:13:54 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=119]]></guid>
    </item><item>
        <title><![CDATA[Majority of patients with mild Alzheimer’s disease will remain excluded from NHS treatment despite revisions to NICE Guidance]]></title>	
        <description><![CDATA[Majority of patients with mild Alzheimer’s disease will remain excluded from NHS treatment despite revisions to NICE Guidance]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=118]]></link>    			 			
        <pubDate>10 Aug 2007 11:13:16 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=118]]></guid>
    </item><item>
        <title><![CDATA[Uncertainty remains for newly diagnosed patients with mild Alzheimer’s disease and their families as the Judicial Review judgement is revealed]]></title>	
        <description><![CDATA[Uncertainty remains for newly diagnosed patients with mild Alzheimer’s disease and their families as the Judicial Review judgement is revealed]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=117]]></link>    			 			
        <pubDate>10 Aug 2007 11:12:29 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=117]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=116]]></link>    			 			
        <pubDate>02 Aug 2007 11:11:56 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=116]]></guid>
    </item><item>
        <title><![CDATA[CNBC interview with Matthew Emmens, CEO, following Shire’s Q2 results (video)]]></title>	
        <description><![CDATA[CNBC interview with Matthew Emmens, CEO, following Shire’s Q2 results (video)]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=115]]></link>    			 			
        <pubDate>31 Jul 2007 11:10:50 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=115]]></guid>
    </item><item>
        <title><![CDATA[Application for Share Listing]]></title>	
        <description><![CDATA[Application for Share Listing]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=114]]></link>    			 			
        <pubDate>27 Jul 2007 11:09:24 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=114]]></guid>
    </item><item>
        <title><![CDATA[2007 guidance upgraded as revenue growth accelerates]]></title>	
        <description><![CDATA[2007 guidance upgraded as revenue growth accelerates]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=113]]></link>    			 			
        <pubDate>26 Jul 2007 11:08:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=113]]></guid>
    </item><item>
        <title><![CDATA[Shire Board Changes]]></title>	
        <description><![CDATA[Shire Board Changes]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=112]]></link>    			 			
        <pubDate>25 Jul 2007 11:07:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=112]]></guid>
    </item><item>
        <title><![CDATA[Second quarter 2007 results – Timing of investor / analyst meeting changed to 14:30 BST / 9:30 EDT]]></title>	
        <description><![CDATA[Second quarter 2007 results – Timing of investor / analyst meeting changed to 14:30 BST / 9:30 EDT]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=111]]></link>    			 			
        <pubDate>19 Jul 2007 11:06:53 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=111]]></guid>
    </item><item>
        <title><![CDATA[Second quarter 2007 results date notification - 26 July 2007]]></title>	
        <description><![CDATA[Second quarter 2007 results date notification - 26 July 2007]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=110]]></link>    			 			
        <pubDate>18 Jul 2007 11:06:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=110]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=109]]></link>    			 			
        <pubDate>02 Jul 2007 11:05:20 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=109]]></guid>
    </item><item>
        <title><![CDATA[Shire Announces Filing of VYVANSE™ (lisdexamfetamine dimesylate) for the Treatment of ADHD in Adults ]]></title>	
        <description><![CDATA[Shire Announces Filing of VYVANSE™ (lisdexamfetamine dimesylate) for the Treatment of ADHD in Adults ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=108]]></link>    			 			
        <pubDate>29 Jun 2007 11:04:31 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=108]]></guid>
    </item><item>
        <title><![CDATA[Shire Demonstrates Commitment To Improving Patient Adherence In End Stage Renal Disease As New Phosphate-Binder FOSRENOL® Launches In Europe]]></title>	
        <description><![CDATA[Shire Demonstrates Commitment To Improving Patient Adherence In End Stage Renal Disease As New Phosphate-Binder FOSRENOL® Launches In Europe]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=107]]></link>    			 			
        <pubDate>25 Jun 2007 11:03:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=107]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=106]]></link>    			 			
        <pubDate>25 Jun 2007 11:02:47 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=106]]></guid>
    </item><item>
        <title><![CDATA[Shire Receives Approvable Letter from FDA for INTUNIV™ (guanfacine) Extended Release, a Nonstimulant for the Treatment of ADHD]]></title>	
        <description><![CDATA[Shire Receives Approvable Letter from FDA for INTUNIV™ (guanfacine) Extended Release, a Nonstimulant for the Treatment of ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=105]]></link>    			 			
        <pubDate>21 Jun 2007 11:01:44 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=105]]></guid>
    </item><item>
        <title><![CDATA[Shire in-licenses JUVISTA® (human TGFβ3) from Renovo]]></title>	
        <description><![CDATA[Shire in-licenses JUVISTA® (human TGFβ3) from Renovo]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=104]]></link>    			 			
        <pubDate>20 Jun 2007 11:00:40 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=104]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=103]]></link>    			 			
        <pubDate>20 Jun 2007 10:59:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=103]]></guid>
    </item><item>
        <title><![CDATA[Results of the Annual General Meeting]]></title>	
        <description><![CDATA[Results of the Annual General Meeting]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=102]]></link>    			 			
        <pubDate>20 Jun 2007 10:58:58 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=102]]></guid>
    </item><item>
        <title><![CDATA[Annual Information Update]]></title>	
        <description><![CDATA[Annual Information Update]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=101]]></link>    			 			
        <pubDate>20 Jun 2007 10:58:11 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=101]]></guid>
    </item><item>
        <title><![CDATA[Goldman Sachs Group and its holdings in Shire]]></title>	
        <description><![CDATA[Goldman Sachs Group and its holdings in Shire]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=100]]></link>    			 			
        <pubDate>19 Jun 2007 10:57:23 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=100]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=99]]></link>    			 			
        <pubDate>01 Jun 2007 10:56:40 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=99]]></guid>
    </item><item>
        <title><![CDATA[Block Listing Six Monthly Return]]></title>	
        <description><![CDATA[Block Listing Six Monthly Return]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=98]]></link>    			 			
        <pubDate>29 May 2007 10:54:46 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=98]]></guid>
    </item><item>
        <title><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a Person Discharging Managerial Responsibilities]]></title>	
        <description><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a Person Discharging Managerial Responsibilities]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=97]]></link>    			 			
        <pubDate>22 May 2007 10:53:39 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=97]]></guid>
    </item><item>
        <title><![CDATA[FDA Issues Approvable Letter for SPD465 (Triple-Bead Mixed Amphetamine Salts) for the Treatment of ADHD in Adults]]></title>	
        <description><![CDATA[FDA Issues Approvable Letter for SPD465 (Triple-Bead Mixed Amphetamine Salts) for the Treatment of ADHD in Adults]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=96]]></link>    			 			
        <pubDate>19 May 2007 10:51:45 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=96]]></guid>
    </item><item>
        <title><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a Person Discharging Managerial Responsibilities]]></title>	
        <description><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a Person Discharging Managerial Responsibilities]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=95]]></link>    			 			
        <pubDate>18 May 2007 10:50:58 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=95]]></guid>
    </item><item>
        <title><![CDATA[Shire to Present New Scientific Data on ADHD Treatment Portfolio at APA Annual Meeting]]></title>	
        <description><![CDATA[Shire to Present New Scientific Data on ADHD Treatment Portfolio at APA Annual Meeting]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=94]]></link>    			 			
        <pubDate>14 May 2007 10:49:52 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=94]]></guid>
    </item><item>
        <title><![CDATA[Shire welcomes early date for Judicial Review of NICE decision on Alzheimer’s treatments]]></title>	
        <description><![CDATA[Shire welcomes early date for Judicial Review of NICE decision on Alzheimer’s treatments]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=93]]></link>    			 			
        <pubDate>11 May 2007 10:49:01 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=93]]></guid>
    </item><item>
        <title><![CDATA[Retirement of Non-Executive Director and notification of the Exercise of an Option and Sale of Shares]]></title>	
        <description><![CDATA[Retirement of Non-Executive Director and notification of the Exercise of an Option and Sale of Shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=92]]></link>    			 			
        <pubDate>11 May 2007 10:48:26 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=92]]></guid>
    </item><item>
        <title><![CDATA[Shire plc announces the Exercise of Over-Allotment Option in relation to Convertible Bond Offering outside the United States and to non-US persons only]]></title>	
        <description><![CDATA[Shire plc announces the Exercise of Over-Allotment Option in relation to Convertible Bond Offering outside the United States and to non-US persons only]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=91]]></link>    			 			
        <pubDate>08 May 2007 10:47:08 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=91]]></guid>
    </item><item>
        <title><![CDATA[VYVANSE™ (lisdexamfetamine dimesylate) Receives Final DEA Schedule Classification, Clearing Way for Launch of First Prodrug Stimulant for Treatment of ADHD]]></title>	
        <description><![CDATA[VYVANSE™ (lisdexamfetamine dimesylate) Receives Final DEA Schedule Classification, Clearing Way for Launch of First Prodrug Stimulant for Treatment of ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=89]]></link>    			 			
        <pubDate>03 May 2007 10:46:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=89]]></guid>
    </item><item>
        <title><![CDATA[VYVANSE™ (lisdexamfetamine dimesylate) Receives Final DEA Schedule Classification, Clearing Way for Launch of First Prodrug Stimulant for Treatment of ADHD]]></title>	
        <description><![CDATA[VYVANSE™ (lisdexamfetamine dimesylate) Receives Final DEA Schedule Classification, Clearing Way for Launch of First Prodrug Stimulant for Treatment of ADHD]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=90]]></link>    			 			
        <pubDate>03 May 2007 10:46:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=90]]></guid>
    </item><item>
        <title><![CDATA[Shire announces the Pricing of US$1,000 million Convertible Bonds due 2014 to be offered outside the United States and to non-US persons only]]></title>	
        <description><![CDATA[Shire announces the Pricing of US$1,000 million Convertible Bonds due 2014 to be offered outside the United States and to non-US persons only]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=88]]></link>    			 			
        <pubDate>02 May 2007 10:45:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=88]]></guid>
    </item><item>
        <title><![CDATA[Shire announces refinancing of bank facilities connected with the recent acquisition of New River through the launch of US$1,000 million Convertible Bonds due 2014 to be offered outside the United States and to non-US persons only]]></title>	
        <description><![CDATA[Shire announces refinancing of bank facilities connected with the recent acquisition of New River through the launch of US$1,000 million Convertible Bonds due 2014 to be offered outside the United States and to non-US persons only]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=87]]></link>    			 			
        <pubDate>02 May 2007 10:44:15 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=87]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=86]]></link>    			 			
        <pubDate>01 May 2007 10:43:22 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=86]]></guid>
    </item><item>
        <title><![CDATA[First quarter results - strong start to the year with upgraded guidance now including New River]]></title>	
        <description><![CDATA[First quarter results - strong start to the year with upgraded guidance now including New River]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=85]]></link>    			 			
        <pubDate>25 Apr 2007 10:42:19 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=85]]></guid>
    </item><item>
        <title><![CDATA[Shire Completes Acquisition of New River]]></title>	
        <description><![CDATA[Shire Completes Acquisition of New River]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=84]]></link>    			 			
        <pubDate>20 Apr 2007 10:41:36 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=84]]></guid>
    </item><item>
        <title><![CDATA[Shire Successfully Completes Tender Offer for New River Shares]]></title>	
        <description><![CDATA[Shire Successfully Completes Tender Offer for New River Shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=83]]></link>    			 			
        <pubDate>18 Apr 2007 10:40:05 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=83]]></guid>
    </item><item>
        <title><![CDATA[FIRST QUARTER 2007 RESULTS DATE NOTIFICATION]]></title>	
        <description><![CDATA[FIRST QUARTER 2007 RESULTS DATE NOTIFICATION]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=82]]></link>    			 			
        <pubDate>17 Apr 2007 10:39:22 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=82]]></guid>
    </item><item>
        <title><![CDATA[Results of Extraordinary General Meeting held on 16 April 2007]]></title>	
        <description><![CDATA[Results of Extraordinary General Meeting held on 16 April 2007]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=81]]></link>    			 			
        <pubDate>16 Apr 2007 10:38:31 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=81]]></guid>
    </item><item>
        <title><![CDATA[Notification of major interests in shares]]></title>	
        <description><![CDATA[Notification of major interests in shares]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=80]]></link>    			 			
        <pubDate>16 Apr 2007 10:37:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=80]]></guid>
    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust ]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=79]]></link>    			 			
        <pubDate>10 Apr 2007 10:35:44 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=79]]></guid>
    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=78]]></link>    			 			
        <pubDate>05 Apr 2007 10:34:57 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=78]]></guid>
    </item><item>
        <title><![CDATA[Movement of shares out of the Employee Benefit Trust]]></title>	
        <description><![CDATA[Movement of shares out of the Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=77]]></link>    			 			
        <pubDate>05 Apr 2007 10:34:13 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=77]]></guid>
    </item><item>
        <title><![CDATA[Shire Executive Annual Incentive Plan]]></title>	
        <description><![CDATA[Shire Executive Annual Incentive Plan]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=76]]></link>    			 			
        <pubDate>04 Apr 2007 10:33:32 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=76]]></guid>
    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=75]]></link>    			 			
        <pubDate>04 Apr 2007 10:32:38 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=75]]></guid>
    </item><item>
        <title><![CDATA[Movement of shares out of the Employee Benefit Trust]]></title>	
        <description><![CDATA[Movement of shares out of the Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=74]]></link>    			 			
        <pubDate>04 Apr 2007 10:31:46 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=73]]></link>    			 			
        <pubDate>03 Apr 2007 10:31:02 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=73]]></guid>
    </item><item>
        <title><![CDATA[Application for share listing]]></title>	
        <description><![CDATA[Application for share listing]]></description>						
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        <pubDate>03 Apr 2007 10:30:17 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=72]]></guid>
    </item><item>
        <title><![CDATA[Shire Executive Annual Incentive Plan]]></title>	
        <description><![CDATA[Shire Executive Annual Incentive Plan]]></description>						
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        <pubDate>02 Apr 2007 10:29:30 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=71]]></guid>
    </item><item>
        <title><![CDATA[Total Voting Rights]]></title>	
        <description><![CDATA[Total Voting Rights]]></description>						
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        <pubDate>02 Apr 2007 10:26:10 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a Non-Executive Director]]></title>	
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        <pubDate>02 Apr 2007 10:25:06 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust ]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust ]]></description>						
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        <pubDate>02 Apr 2007 10:23:59 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
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        <pubDate>29 Mar 2007 10:23:08 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
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        <pubDate>28 Mar 2007 10:22:32 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a Person Discharging Managerial Responsibilities]]></title>	
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        <pubDate>28 Mar 2007 10:21:45 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Judicial Review of NICE decision ]]></title>	
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        <pubDate>27 Mar 2007 10:21:04 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
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        <pubDate>27 Mar 2007 10:20:16 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Notice of EGM ]]></title>	
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        <pubDate>26 Mar 2007 10:19:39 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
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        <pubDate>26 Mar 2007 10:14:46 GMT</pubDate>
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    </item><item>
        <title><![CDATA[IFRS results for the year ending December 31, 2006]]></title>	
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        <pubDate>23 Mar 2007 10:13:44 GMT</pubDate>
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    </item><item>
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        <pubDate>23 Mar 2007 10:12:56 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Holding(s) in Company]]></title>	
        <description><![CDATA[Holding(s) in Company]]></description>						
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        <pubDate>22 Mar 2007 10:12:09 GMT</pubDate>
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        <title><![CDATA[Holding(s) in Company]]></title>	
        <description><![CDATA[Holding(s) in Company]]></description>						
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        <pubDate>22 Mar 2007 10:11:24 GMT</pubDate>
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        <title><![CDATA[Notification of the Exercise of an Option and Sale of Shares by a Director]]></title>	
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        <pubDate>22 Mar 2007 10:10:42 GMT</pubDate>
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        <pubDate>22 Mar 2007 10:09:58 GMT</pubDate>
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    </item><item>
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        <description><![CDATA[ADDERALL XR® - Shire Files Suit against Colony Pharmaceuticals, Inc., Actavis, Inc. and Actavis Group hf]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=54]]></link>    			 			
        <pubDate>21 Mar 2007 10:08:49 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Shire begins external search for President of successful Human Genetic Therapies business, on retirement of David Pendergast at the end of 2007]]></title>	
        <description><![CDATA[Shire begins external search for President of successful Human Genetic Therapies business, on retirement of David Pendergast at the end of 2007]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=53]]></link>    			 			
        <pubDate>20 Mar 2007 10:07:35 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Shire Announces Expiration of Hart-Scott-Rodino Waiting Period]]></title>	
        <description><![CDATA[Shire Announces Expiration of Hart-Scott-Rodino Waiting Period]]></description>						
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        <pubDate>19 Mar 2007 10:06:29 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Correction to Purchase of Shares by Employee Benefit Trust]]></title>	
        <description><![CDATA[Correction to Purchase of Shares by Employee Benefit Trust]]></description>						
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        <pubDate>19 Mar 2007 10:05:15 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
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        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=50]]></link>    			 			
        <pubDate>16 Mar 2007 05:23:09 GMT</pubDate>
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    </item><item>
        <title><![CDATA[New Human Cell-Produced Treatment for Anaemia Associated with Chronic Kidney Disease Now Available, Shire’s launch of DYNEPO® (epoetin delta) begins across Europe]]></title>	
        <description><![CDATA[New Human Cell-Produced Treatment for Anaemia Associated with Chronic Kidney Disease Now Available, Shire’s launch of DYNEPO® (epoetin delta) begins across Europe]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=49]]></link>    			 			
        <pubDate>15 Mar 2007 05:21:03 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=48]]></link>    			 			
        <pubDate>15 Mar 2007 05:18:29 GMT</pubDate>
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    </item><item>
        <title><![CDATA[Purchase of shares by employee benefit trust]]></title>	
        <description><![CDATA[Purchase of shares by employee benefit trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=47]]></link>    			 			
        <pubDate>14 Mar 2007 05:17:39 GMT</pubDate>
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        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
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        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=46]]></link>    			 			
        <pubDate>13 Mar 2007 05:16:34 GMT</pubDate>
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        <pubDate>12 Mar 2007 05:15:40 GMT</pubDate>
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        <pubDate>09 Mar 2007 05:14:49 GMT</pubDate>
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        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=43]]></link>    			 			
        <pubDate>08 Mar 2007 05:13:51 GMT</pubDate>
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        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=42]]></link>    			 			
        <pubDate>06 Mar 2007 05:12:46 GMT</pubDate>
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        <pubDate>06 Mar 2007 05:10:54 GMT</pubDate>
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    </item><item>
        <title><![CDATA[UK launch expands global reach of FOSRENOL®]]></title>	
        <description><![CDATA[UK launch expands global reach of FOSRENOL®]]></description>						
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        <pubDate>05 Mar 2007 05:09:18 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=40]]></guid>
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        <title><![CDATA[Holding(s) in Company]]></title>	
        <description><![CDATA[Holding(s) in Company]]></description>						
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        <pubDate>02 Mar 2007 05:07:55 GMT</pubDate>
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    </item><item>
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        <description><![CDATA[Purchase of Shares by Employee Benefit Trust]]></description>						
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        <pubDate>02 Mar 2007 05:06:44 GMT</pubDate>
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        <title><![CDATA[Purchase of Shares by Employee Benefit Trust]]></title>	
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        <pubDate>02 Mar 2007 05:04:53 GMT</pubDate>
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        <title><![CDATA[Director/PDMR Shareholding ]]></title>	
        <description><![CDATA[Director/PDMR Shareholding ]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=36]]></link>    			 			
        <pubDate>28 Feb 2007 05:03:58 GMT</pubDate>
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        <title><![CDATA[Holding(s) in Company]]></title>	
        <description><![CDATA[Holding(s) in Company]]></description>						
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        <pubDate>28 Feb 2007 05:02:39 GMT</pubDate>
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        <title><![CDATA[Holding(s) in Company]]></title>	
        <description><![CDATA[Holding(s) in Company]]></description>						
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        <pubDate>28 Feb 2007 05:01:49 GMT</pubDate>
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        <title><![CDATA[Holding(s) in Company]]></title>	
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        <pubDate>28 Feb 2007 05:00:41 GMT</pubDate>
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        <title><![CDATA[Holding(s) in Company]]></title>	
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        <pubDate>28 Feb 2007 04:59:42 GMT</pubDate>
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        <pubDate>28 Feb 2007 04:58:35 GMT</pubDate>
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        <title><![CDATA[Movement of shares out of the Employee Benefit Trust]]></title>	
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        <pubDate>27 Feb 2007 04:57:43 GMT</pubDate>
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        <pubDate>23 Feb 2007 04:56:43 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=29]]></guid>
    </item><item>
        <title><![CDATA[Director/PDMR Shareholding]]></title>	
        <description><![CDATA[Director/PDMR Shareholding]]></description>						
        <link><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=28]]></link>    			 			
        <pubDate>23 Feb 2007 04:55:19 GMT</pubDate>
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        <title><![CDATA[Employee Benefit Trust announcement]]></title>	
        <description><![CDATA[Employee Benefit Trust announcement]]></description>						
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        <pubDate>23 Feb 2007 04:54:11 GMT</pubDate>
        <guid><![CDATA[http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=27]]></guid>
    </item><item>
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        <description><![CDATA[FOSRENOL® launches in United Kingdom today]]></description>						
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        <pubDate>22 Feb 2007 04:52:24 GMT</pubDate>
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        <title><![CDATA[Director/PDMR Shareholding]]></title>	
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        <pubDate>22 Feb 2007 04:51:35 GMT</pubDate>
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        <title><![CDATA[Shire agrees to acquire new river to gain full control of Vyvanseâ¢, its future flagship product for ADHD]]></title>	
        <description><![CDATA[Shire agrees to acquire new river to gain full control of Vyvanseâ¢, its future flagship product for ADHD]]></description>						
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        <pubDate>20 Feb 2007 04:50:17 GMT</pubDate>
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        <title><![CDATA[Shire announces $800 million equity financing in connection with Acquisition Of New River]]></title>	
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        <pubDate>20 Feb 2007 04:40:20 GMT</pubDate>
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        <title><![CDATA[Result of equity placing]]></title>	
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        <pubDate>20 Feb 2007 10:02:57 GMT</pubDate>
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        <title><![CDATA[Results for the twelve months to December 31, 2006 - On time execution of operating plan delivers strong 2006 performance]]></title>	
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        <pubDate>20 Feb 2007 10:01:42 GMT</pubDate>
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        <title><![CDATA[Total Voting Rights]]></title>	
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        <pubDate>15 Feb 2007 09:59:55 GMT</pubDate>
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        <title><![CDATA[Full Year 2006 Results Date Notification - 23 February 2007]]></title>	
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        <pubDate>14 Feb 2007 09:58:54 GMT</pubDate>
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        <title><![CDATA[Movement of shares out of the Employee Benefit Trust]]></title>	
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        <pubDate>12 Feb 2007 09:57:54 GMT</pubDate>
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        <title><![CDATA[Goldman Sachs Group and its holdings in Shire]]></title>	
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        <pubDate>25 Jan 2007 09:46:54 GMT</pubDate>
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        <title><![CDATA[Shire licenses the North American rights for SPD754]]></title>	
        <description><![CDATA[Shire licenses the North American rights for SPD754]]></description>						
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        <pubDate>23 Jan 2007 09:44:05 GMT</pubDate>
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        <title><![CDATA[Total Voting Rights]]></title>	
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        <pubDate>18 Jan 2007 09:43:08 GMT</pubDate>
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        <pubDate>12 Jan 2007 09:39:46 GMT</pubDate>
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        <title><![CDATA[ELAPRASE® for the treatment of Hunter syndrome approved by the European Commission]]></title>	
        <description><![CDATA[ELAPRASE® for the treatment of Hunter syndrome approved by the European Commission]]></description>						
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        <pubDate>11 Jan 2007 09:34:04 GMT</pubDate>
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