R&D projects

Shire has a total of 17 projects in full development of which 14 are in Phase 2 or beyond.

Indication Project Phase Estimated submission Estimated launch
SPECIALTY PHARMA
ADHD INTUNIV Registration H1-2009 2009
ADHD-EU DAYTRANA-EU Registration 2009
ADHD-US adolescent DAYTRANA-US 3 H2-2009 2010
ADHD-EU VYVANSE 3 2011
Chronic Kidney disease FOSRENOL 3 2009
Diverticulitis LIALDA 3 2012-2015
Celiac disease SPD550 2 2012-2015
Prevention and reduction of scarring AVOTERMIN 2 2012-2015
HUMAN GENETIC THERAPIES
Hereditary angioedema FIRAZYR (US) 3 2011
Gaucher disease VELAGLUCERASE ALFA 3 H2-2009 2010
Metachromatic Leukodystrophy HGT-1111 (METAZYM) 2 2012-2015
Fabry disease HGT-3310 (AMIGAL) 2 2012-2015
Gaucher disease HGT-3410 (PLICERA) 2 2012-2015
Pompe disease HGT-3510* 2 2012-2015
Hunter syndrome CNS HGT-2310 1 2012-2015
Sanfilippo A syndrome HGT-1410 Pre-clinical 2012-2015
Krabbe disease HGT&-2610 Pre-clinical 2012-2015
*Currently on clinical hold in the US.