What responsibility means to us...

We have rolled out a global building management system that covers all our office facilities outside the U.S. We will continue to refine and improve the system in 2012.

We achieved a 6% reduction in electricity consumption and a 23% reduction in gas consumption in our Unity Place facility in the U.K. This was achieved through:

• Changing light bulbs from 50w to 7w LED
• Installing more motion controlled lighting 
• Putting timers on hot water machines so they are not left running overnight 
• Installing inverters on air pumps, water pumps, gas pumps and fans. The inverters hold back frequency typically on the fans from 50Hz to 45Hz 
• Reducing plant running time by about 5% 
• Installing new chillers 

For our new Research & Development (R&D) facility in Lexington MA, the construction submittal for Leadership in Energy and Design (LEED) Certification was made in January 2012. 

At our Alewife, Massachusetts (U.S.) facility where we under took a major renovation, we submit an application for LEED certification.

In January 2012 we received confirmation that Project Atlas, our new state-of-the art manufacturing facility in Massachusetts, had attained LEED certification under LEED_NCv2009. We expect to receive formal recognition from the United States Green Building Council (USGBC) in Q1 2012. The Project Atlas plant is the first in the world to embrace single-use technology for biotechnology manufacturing in a commercial sterile train at the 2,000 Liter scale.  Shire’s utilization of single-use technology in the manufacturing process requires approximately 80% less water and 50% less energy as compared to conventional equipment of the same functionality and operational pattern.

In 2011, our HGT business in the U.S. diverted 284 tons of material from disposal to recycling and reuse.  This is an increase in 136 tons compared with 2010.  Recycling has helped Lexington, MA  facilities reduce its carbon footprint by 188.82 metric tons of carbon equivalent by:

• Expanding comingled recycling:  previously, we only collected “redeemable” bottles and cans for recycling.  The new program allows all bottles, cans, and rigid plastic containers to be recycled together. 
• Roller bottle* recycling:  we set up an innovative program to divert the “roller bottle material” to recycling.  This material consists of roller bottles and red disposal bags which have been autoclaved** and then run through a chipping machine.  We have a vendor that picks up the chipped material which is sold to a plastic supplier who separates the hard polystyrene (roller bottle) from the LDPE (red bag) using a water flotation system.  Once separated, the materials are sold to a variety of manufacturers who make products such as CD cases, traffic cones, and plastic lumber.  Since beginning the program, we have diverted over 13 tons to recycling.  This work will result in diverting more than 60,000 roller bottles annually that would have otherwise contributed to landfill and greatly decrease the carbon footprint associated with transportation of the roller bottle waste 
• Café composting:  The café at Lexington, MA kicked off a “front of the house” composting program.  Most of the products used by the café are compostable, and innovative bins and signage are helping divert much of the waste to composting.
   

We became a corporate sponsor of the Green Supplier Network (GSN). We engaged four suppliers who registered with GSN; three have already completed “Lean and Green” GSN assessments of their manufacturing operations focused on minimizing waste generation and maximizing production efficiencies. These GSN partners are now working on actions identified during the assessments to reduce their environmental impacts.

In the UK, our efforts to improve recycling paid off. We reduced by 26% the amount of waste we sent to landfill, and increased waste sent to recycling by more than 21%. Our efforts included introduction of recycling all our kitchen waste.

We initiated recycling of paper and card and plastic in our German facility.

At our Chesterbrook, PA (US) facility:

• We worked with our main office supplier to eliminate packaging waste. We now have all our office suppliers delivered in reusable totes that are taken back by the supplier, eliminating hundreds of cardboard boxes from our waste stream. We are also promoting purchase of environmentally-friendly office products.
• We participated in the Greater Philadelphia Bike to Work challenge. Our colleagues biked 826 miles saving 37 gallons of fuel and prevented 727 pounds of CO2 emissions into our air by not driving their cars to work.
• We increased battery recycling by 137% over  2010.
• We purchased 198 MWH of Renewable Energy Credits (wind) to green our energy usage.
• We composted over 16,000 pounds of food waste, diverting it from landfill.

We continue to refine and improve our HSE management. We undertook gap analyses of our systems at all our manufacturing and distribution facilities and have active action plans that address gaps and improvement opportunities identified.

Third-party HSE compliance audits were undertaken at all our manufacturing and distribution facilities. In addition HSE conducted regulatory assessments at our facilities in Germany, Ireland, France, Canada, Argentina, and Brazil