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22 Sep 2009
Director/PDMR Shareholding

September 22, 2009 - Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company (the “Company”), announces that on September 21, 2009, Ms Tatjana May, a Person Discharging Managerial Responsibility, was granted the following options under the Shire Sharesave Scheme.

Type of Security No. of Ordinary Shares Exercise Price
Ordinary Shares 1,108 £8.19

Following this transaction Ms May retains options, stock appreciation rights and performance shares over a total of 661,546 shares in the Company

This notification is to satisfy the Company’s obligations under 3.1.4(R)(1)(a) of the Disclosure and Transparency Rules.

Tony Guthrie
Deputy Company Secretary
For further information please contact:

Investor Relations Cléa Rosenfeld (Rest of the World) +44 1256 894 160
 Eric Rojas (North America) +1 617 551 9715

Notes to editors


Shire’s strategic goal is to become the leading specialty biopharmaceutical company that focuses on meeting the needs of the specialist physician.  Shire focuses its business on attention deficit hyperactivity disorder (ADHD), human genetic therapies (HGT) and gastrointestinal (GI) diseases as well as opportunities in other therapeutic areas to the extent they arise through acquisitions.  Shire’s in-licensing, merger and acquisition efforts are focused on products in specialist markets with strong intellectual property protection and global rights.  Shire believes that a carefully selected and balanced portfolio of products with strategically aligned and relatively small-scale sales forces will deliver strong results.

For further information on Shire, please visit the Company’s website:

22 Sep 2009 Director/PDMR Shareholding (18KB PDF)

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